A Prospective Study to Collect Images in Patients Treated With Iodine-131 as Part of a European Research Project in Radiation Protection. (MEDIRAD)
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|ClinicalTrials.gov Identifier: NCT03986437|
Recruitment Status : Recruiting
First Posted : June 14, 2019
Last Update Posted : May 8, 2020
This trial is a prospective, non-interventional, monocentric study aiming to collect standard of care imaging of patients treated with Iodine-131 for the determination of dosimetric studies.
Data from this study will be collected as part of an European research project called MEDIRAD.
The overall objectives of this project are to enhance the scientific bases and clinical practice of radiation protection in the medical field, and more specifically to develop and implement the tools necessary to establish the range of absorbed doses delivered to healthy organs in patients undergoing thyroid ablation and the threshold absorbed dose required for thyroid ablation. This will enable patient specific treatment planning that will minimize risk to the patient while ensuring a successful outcome and will facilitate development of a large scale epidemiological study of the effect of low absorbed doses from irradiation of normal organs with internal sources of radionuclides.
Patients will be followed as part of their standard of care. Imaging (SPECT/CT (Single Photon Emission Computed Tomography-Computerized Tomography) and Whole Body scintigraphy) performed at 48 hours post Iodine-131 treatment will be collected. Measures of external gamma radiation will also be collected in the European database.
|Condition or disease|
|Differentiated Thyroid Cancer|
|Study Type :||Observational|
|Estimated Enrollment :||25 participants|
|Official Title:||A Prospective Study to Collect Images in Patients Treated With Iodine-131 as Part of a European Research Project in Radiation Protection.|
|Actual Study Start Date :||January 13, 2020|
|Estimated Primary Completion Date :||March 2021|
|Estimated Study Completion Date :||March 2021|
- Number of patients with interpretable images [ Time Frame: 1 week per patient ]
- Rate of radiation dose [ Time Frame: 1 week per patient ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03986437
|Contact: Frédéric COURBON||+33 5 31 15 55 26||Courbon.firstname.lastname@example.org|
|Contact: Frédéric COURBON +33 5 31 15 55 26 Courbon.email@example.com|