The Vascular Changes of Scars With Laser Therapy
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|ClinicalTrials.gov Identifier: NCT03986346|
Recruitment Status : Recruiting
First Posted : June 14, 2019
Last Update Posted : July 10, 2019
|Condition or disease||Intervention/treatment||Phase|
|Scar||Device: pulsed dye laser Other: pressure therapy||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||40 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Masking Description:||Participants who receive pulsed dye laser and participants who receive pressure therapy will be recruited from 2 different hospitals separately.|
|Official Title:||The Vascular Changes of Scars With Receiving Pulsed Dye Laser|
|Actual Study Start Date :||June 21, 2019|
|Estimated Primary Completion Date :||February 29, 2020|
|Estimated Study Completion Date :||February 29, 2020|
Experimental: Laser group
Participants in this group receive pulsed dye laser to treat the scar.
Device: pulsed dye laser
The scar will receive PDL 595 nm using a 7 mm spot size. First treatment will be within 1 year post injury.
Active Comparator: Pressure therapy group
Participants in this group receive pressure therapy to treat the scar.
Other: pressure therapy
Pressure garment will be prescribed for participants to manage scars.
- scar redness [ Time Frame: 3 months ]Dermoscopy captures the scar photo and measures degrees of scar redness.
- scar blood flow [ Time Frame: 3 months ]Ultrasound measures blood flow in scar tissues
- scar thickness [ Time Frame: 3 months ]Ultrasound measures scar thickness.
- patient and observer scar assessment scale (POSAS) [ Time Frame: 3 months ]The POSAS measures scar vascularity, pigmentation, pigmentation, thickness, relief, pliability and surface area. Every parameter ranges from 1 to 10, and higher score indicates worse scar performance in that parameter. The total score of POSAS is calculated by summing all the parameters' scores.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03986346
|Contact: Huan DENGfirstname.lastname@example.org|
|Prince of Wales Hospital||Recruiting|
|Hong Kong, Hong Kong|
|Contact: Teresa Tan|
|Principal Investigator:||Cecilia Li-tsang||The Hong Kong Polytechnic University|