Preoperative Pulmonary Systolic Pressure and Outcome After Non-cardiac Surgery:Threshold Analysis
|ClinicalTrials.gov Identifier: NCT03974919|
Recruitment Status : Completed
First Posted : June 5, 2019
Last Update Posted : July 9, 2019
|Condition or disease||Intervention/treatment|
|Pulmonary Hypertension||Other: NO intervention required|
The linear or nonlinear relationship of pulmonary systolic pressure and cardiovascular and kidney outcome after non-cardiac surgery is unknown. This study is to explore the relationship of the two and try to identify the possible threshold of pulmonary systolic pressure for major cardio-vascular events after non-cardiac surgery.
Patients with preoperative cardio-echogram under going non-cardiac surgery were collected. The postoperative major cardiovascular, cerebral and kidney events were also identified and collected. Other data including peri-operative information and surgeries and anesthesia data were gathered.
Logistic regression models were built and selected. Independent risk factors relative to postoperative major cardiovascular and cerebral events were screened and identified. Odds ratio, relative risk and relative risk ratio of varies dichomitus cut points were calculated, trend breakpoint were identified, propensity score analysis were also done for causal inference.
|Study Type :||Observational|
|Actual Enrollment :||19000 participants|
|Official Title:||Preoperative Pulmonary Systolic Pressure and Outcome After Non-Cardiac Surgery:Threshold Analysis|
|Actual Study Start Date :||May 1, 2019|
|Actual Primary Completion Date :||June 10, 2019|
|Actual Study Completion Date :||June 11, 2019|
- Other: NO intervention required
NO intervention required
- major adverse events [ Time Frame: 30 days postoperatively in hospital ]cardiac infarction, heart failure, cardiac death, stroke, acute kidney injury
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03974919
|First hospital Peking University|
|Beijing, Beijing, China, 100034|