Subconjunctival Injection of Allogeneic Mesenchymal Stem Cells in Severe Ocular Chemical Burn (SyMbOL)
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT03967275|
Recruitment Status : Recruiting
First Posted : May 30, 2019
Last Update Posted : April 9, 2021
The objective of this pre-clinical study is to demonstrate the robustness of Bone Marrow derived Mesenchymal Stem Cells (BM-MSC) production, to treat patients with severe eye burns.
For bone marrow donors who agree to participate, a 10 ml BM sample will be collected apart the 1 liter BM dedicated to transplantation.
A maximum of three donors of allogeneic BM-MSCs will be included. A ready-to-use BM-MSC suspension will be produced and stored for 10 years to accumulate data about stability of cryopreserved cells.
|Condition or disease||Intervention/treatment|
|Bone Marrow Donor||Other: bone marrow harvest|
|Study Type :||Observational|
|Estimated Enrollment :||3 participants|
|Official Title:||Subconjunctival Injection of Allogeneic Mesenchymal Stem Cells in Severe Ocular Chemical Burn SyMbOL Pre Clinical Study|
|Actual Study Start Date :||September 9, 2020|
|Estimated Primary Completion Date :||September 2021|
|Estimated Study Completion Date :||September 2030|
- Other: bone marrow harvest
During bone marrow harvest, an additional 10 mL sample will be collected for the study.
- The number of donors needed to obtain 3 BM harvest. [ Time Frame: 6 months ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03967275
|Contact: Eric Gabisonemail@example.com|
|Contact: Amélie Yavchitzfirstname.lastname@example.org|
|Saint Louis Hospital, APHP||Recruiting|
|Paris, France, 75010|
|Contact: Camille MAHEUX email@example.com|