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Effects of an Acute and Chronic Training Protocol Associated to the Inter-set Velocity Loss

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ClinicalTrials.gov Identifier: NCT03964519
Recruitment Status : Not yet recruiting
First Posted : May 28, 2019
Last Update Posted : May 29, 2019
Sponsor:
Information provided by (Responsible Party):
Alejandro Muñoz López, University of Seville

Brief Summary:
This study evaluates different performance, physiological and neuromuscular changes after acute and chronic resistance training intervention in physically active men. The participants will train with a single exercise (full squat) and will be monitored with a linear encoder. The experiment will consist of between 3 to 6 sets between 70% to 85% of 1RM in the full squat exercise. Two main groups will form the intervention: one group will perform inter-set repetitions until there will be a 20% of velocity loss compared to the first repetition, while the second group will have a 40% of velocity loss.

Condition or disease Intervention/treatment Phase
Healthy Other: Acute changes Other: Chronic changes Other: Familiarization Not Applicable

Detailed Description:

The main dependent variables and instruments will be:

  1. Tensyomiography: neuromuscular properties of the vastus lateral (VL), rectus femoris (RF) and vastus medialis (VM) from the dominant leg.
  2. Force platform: kinetic variables in relation to a countermovement jump.
  3. Near-infrared spectrography: oxygen saturation in the VL and VM.
  4. Termographic camera: low limbs temperatura.
  5. Linear encoder: mean propulsive velocity from each repetition
  6. Electromyography: amplitude and frequency parameters related to a knee extension maximum voluntary contraction test.
  7. Strain gauge: maximum isometric force.

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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 30 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single (Participant)
Primary Purpose: Other
Official Title: Neuromuscular, Physiological and Performance Changes After an Acute and Chronic Training Protocol Associated to the Inter-set Velocity Loss
Estimated Study Start Date : July 1, 2019
Estimated Primary Completion Date : August 30, 2019
Estimated Study Completion Date : September 15, 2019

Arm Intervention/treatment
Experimental: 20% velocity loss
This group will train with a variable number of repetitions during each set. The group will stop the set once the mean propulsive velocity will be 20% less compared to the first repetition.
Other: Acute changes
In a crossover design, participants will be randomized to perform on Day 1, 3 sets of repetitions (depending on each treatment group) at 70% or 1RM in the full squat exercise. 48-h later, same will be performed but in the contrary crossover arm.

Other: Chronic changes
In a randomized control trial, participants will train during 6 weeks the full squat exercise, 2 days in the week (minimum between-days rest of 48h). Intensity will vary from 70% to 85 of 1RM, and training volume from 3 to 6 sets.

Other: Familiarization
Prior to any intervention, all participants will perform a familiarization of the exercise session, together with a progressive resistance test to estimate the 1 RM

Experimental: 40% velocity loss
This group will train with a variable number of repetitions during each set. The group will stop the set once the mean propulsive velocity will be 40% less compared to the first repetition.
Other: Acute changes
In a crossover design, participants will be randomized to perform on Day 1, 3 sets of repetitions (depending on each treatment group) at 70% or 1RM in the full squat exercise. 48-h later, same will be performed but in the contrary crossover arm.

Other: Chronic changes
In a randomized control trial, participants will train during 6 weeks the full squat exercise, 2 days in the week (minimum between-days rest of 48h). Intensity will vary from 70% to 85 of 1RM, and training volume from 3 to 6 sets.

Other: Familiarization
Prior to any intervention, all participants will perform a familiarization of the exercise session, together with a progressive resistance test to estimate the 1 RM

Placebo Comparator: Control group
This group will be just tested as a control group.
Other: Chronic changes
In a randomized control trial, participants will train during 6 weeks the full squat exercise, 2 days in the week (minimum between-days rest of 48h). Intensity will vary from 70% to 85 of 1RM, and training volume from 3 to 6 sets.

Other: Familiarization
Prior to any intervention, all participants will perform a familiarization of the exercise session, together with a progressive resistance test to estimate the 1 RM




Primary Outcome Measures :
  1. Contraction time [ Time Frame: 7 weeks ]
    Time between 10% to 90% on the displacement-time curve assessed with the Tensiomiograhpy

  2. Maximum displacement [ Time Frame: 7 weeks ]
    Maximum displacement point the displacement-time curve assessed with the Tensiomiograhpy


Secondary Outcome Measures :
  1. Kinetic variables in the jump [ Time Frame: 7 weeks ]
    Kinetic variables related to the force-time curve registered with the force platform during jumps

  2. Muscle tissue oxygen [ Time Frame: 7 weeks ]
    Oxygen in the muscle tissue assessed via near-infrared spectroscopy

  3. Muscle temperature [ Time Frame: 7 weeks ]
    Low limb muscles temperature assessed with a termographic camera

  4. Mean propulsive velocity [ Time Frame: 7 weeks ]
    Individual repetitions mean propulsive velocity during the full squat exercise, assessed with a linear encoder

  5. Amplitude (RMS) and frequency outputs [ Time Frame: 7 weeks ]
    Muscle electrical activity assessed with an EMG

  6. Peak isometric force [ Time Frame: 7 weeks ]
    Maximum force achieved during a knee extension at 120º



Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 30 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • To be healthy
  • Without injuries or actual illnesses
  • More than 2 years of experience in resistance training or federative sports

Exclusion Criteria:

  • To be sick or injured
  • To have programmed during the intervention phase a dramatic change in the lifestyle

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03964519


Contacts
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Contact: Jesus Gustazo Ponce, PhD +34 658 87 41 34 jesusgustavo.ponce@uca.es
Contact: Alejandro Muñoz López, PhD 0034 699661447 amunoz26@us.es

Sponsors and Collaborators
Alejandro Muñoz López
Investigators
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Study Director: Alejandro Muñoz López, PhD Internship
Principal Investigator: Jesus Gustavo Ponce, PhD Professor
Publications:

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Responsible Party: Alejandro Muñoz López, Associate Professor, University of Seville
ClinicalTrials.gov Identifier: NCT03964519    
Other Study ID Numbers: TMG_velocity_lost
First Posted: May 28, 2019    Key Record Dates
Last Update Posted: May 29, 2019
Last Verified: May 2019
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Alejandro Muñoz López, University of Seville:
velocity loss
Tensiomiography
resistance training