High-intensity Interval Training After Stroke
|ClinicalTrials.gov Identifier: NCT03942588|
Recruitment Status : Completed
First Posted : May 8, 2019
Last Update Posted : May 9, 2019
|Condition or disease||Intervention/treatment||Phase|
|Stroke, Ischemic Stroke Hemorrhagic||Behavioral: High-intensity interval training||Not Applicable|
Stroke is the main cause of serious, long-term disability among Americans. The effects of a stroke make it difficult to participate in routine, daily activities so people become seriously deconditioned after a stroke. This increases the chances of having another stroke and it also increases the risk of death. Even a small increase in aerobic capacity reduces these risks, making aerobic training an important component of post-stroke management.
Twenty to 60 minutes of moderate-intensity exercise on most days of the week is recommended for people with cardiovascular disease, but this is not very practical for many people after a stroke, who need to practice functional tasks like using the impaired arm and improving walking and balance. Another problem is that even when people do participate in aerobic training after a stroke, the improvements in aerobic capacity are sometimes surprisingly small. It is possible that the intensity of the training program was inadequate to improve aerobic capacity in some interventions. High-intensity interval training, in which people alternate between short, intense bouts of exercise and recovery bouts within the session, may be a way to improve aerobic capacity after a stroke with a more feasible training schedule that leaves time to practice functional skills too. High-intensity interval training on a treadmill might be appropriate to improve aerobic capacity and walking ability.
This non-randomized, non-blinded pilot study was designed to assess the feasibility of ten weeks of high-intensity interval training (HIIT) using treadmill training for adults with impaired walking who were at least 6 months post-stroke.
A secondary objective was to measure change in aerobic capacity, and a tertiary objective was to measure functional change in self-selected walking speed and leg strength as a result of the intervention.
10 participants completed HIIT intervention while 5 participants served as controls and received no intervention, but completed both baseline and post-testing sessions.
HIIT participants completed twice-weekly, 35-minute training sessions in a research laboratory for 10 consecutive weeks. At baseline and 12 weeks, all participants completed a graded exercise test, 10-meter walk test at self-selected and fastest, safe overground walking speeds, and a 30-second sit-to-stand test.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||17 participants|
|Intervention Model:||Parallel Assignment|
|Intervention Model Description:||Exercise Intervention group and Usual Activity Control group|
|Masking:||None (Open Label)|
|Official Title:||High-intensity Interval Training for Adults With Chronic Stroke Impairments: A Pilot Feasibility Study|
|Actual Study Start Date :||September 24, 2014|
|Actual Primary Completion Date :||June 8, 2018|
|Actual Study Completion Date :||June 8, 2018|
Experimental: High-intensity interval training
Twice-weekly supervised high-intensity interval treadmill training in a laboratory setting for 10 weeks.
Behavioral: High-intensity interval training
No Intervention: Control
Usual activities for 10 weeks
- Change in Aerobic Capacity [ Time Frame: Baseline and 12 weeks ]Whole-body oxygen consumption measured via a graded exercise test
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03942588
|Principal Investigator:||Pamela R Bosch, PhD||Northern Arizona University|