High-intensity Interval Training After Stroke
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|ClinicalTrials.gov Identifier: NCT03942588|
Recruitment Status : Completed
First Posted : May 8, 2019
Last Update Posted : May 9, 2019
|Condition or disease||Intervention/treatment||Phase|
|Stroke, Ischemic Stroke Hemorrhagic||Behavioral: High-intensity interval training||Not Applicable|
Stroke is the main cause of serious, long-term disability among Americans. The effects of a stroke make it difficult to participate in routine, daily activities so people become seriously deconditioned after a stroke. This increases the chances of having another stroke and it also increases the risk of death. Even a small increase in aerobic capacity reduces these risks, making aerobic training an important component of post-stroke management.
Twenty to 60 minutes of moderate-intensity exercise on most days of the week is recommended for people with cardiovascular disease, but this is not very practical for many people after a stroke, who need to practice functional tasks like using the impaired arm and improving walking and balance. Another problem is that even when people do participate in aerobic training after a stroke, the improvements in aerobic capacity are sometimes surprisingly small. It is possible that the intensity of the training program was inadequate to improve aerobic capacity in some interventions. High-intensity interval training, in which people alternate between short, intense bouts of exercise and recovery bouts within the session, may be a way to improve aerobic capacity after a stroke with a more feasible training schedule that leaves time to practice functional skills too. High-intensity interval training on a treadmill might be appropriate to improve aerobic capacity and walking ability.
This non-randomized, non-blinded pilot study was designed to assess the feasibility of ten weeks of high-intensity interval training (HIIT) using treadmill training for adults with impaired walking who were at least 6 months post-stroke.
A secondary objective was to measure change in aerobic capacity, and a tertiary objective was to measure functional change in self-selected walking speed and leg strength as a result of the intervention.
10 participants completed HIIT intervention while 5 participants served as controls and received no intervention, but completed both baseline and post-testing sessions.
HIIT participants completed twice-weekly, 35-minute training sessions in a research laboratory for 10 consecutive weeks. At baseline and 12 weeks, all participants completed a graded exercise test, 10-meter walk test at self-selected and fastest, safe overground walking speeds, and a 30-second sit-to-stand test.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||17 participants|
|Intervention Model:||Parallel Assignment|
|Intervention Model Description:||Exercise Intervention group and Usual Activity Control group|
|Masking:||None (Open Label)|
|Official Title:||High-intensity Interval Training for Adults With Chronic Stroke Impairments: A Pilot Feasibility Study|
|Actual Study Start Date :||September 24, 2014|
|Actual Primary Completion Date :||June 8, 2018|
|Actual Study Completion Date :||June 8, 2018|
Experimental: High-intensity interval training
Twice-weekly supervised high-intensity interval treadmill training in a laboratory setting for 10 weeks.
Behavioral: High-intensity interval training
No Intervention: Control
Usual activities for 10 weeks
- Change in Aerobic Capacity [ Time Frame: Baseline and 12 weeks ]Whole-body oxygen consumption measured via a graded exercise test
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03942588
|Principal Investigator:||Pamela R Bosch, PhD||Northern Arizona University|