Prognostic Biomarker for CRC (PROMOTE)
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT03928652|
Recruitment Status : Recruiting
First Posted : April 26, 2019
Last Update Posted : April 26, 2019
|Condition or disease|
This is a prospective observational study. Tumor tissue specimens and surgical specimens are obtained from the Sixth Affiliated Hospital, Sun Yat-sen University. The samples are analyzed for biomarkers. The biomarkers are correlated with clinical outcomes (failure-free survival, overall survival, tumor response to treatment (e.g. tumor regression grade for rectal cancer), distant metastasis, recurrence and death).
The aim of the analysis is to explore potential biomarkers and validate the predictive and prognostic value of molecular signature in . This will lead to the definition of risk groups and stratification of patients and will help to precision medicine of colorectal cancer.
|Study Type :||Observational|
|Estimated Enrollment :||1050 participants|
|Official Title:||Prospective Study for Prognostic And Predictive Biomarkers of Colorectal Cancer|
|Actual Study Start Date :||April 24, 2019|
|Estimated Primary Completion Date :||April 2023|
|Estimated Study Completion Date :||December 2023|
- Failure-free Survival [ Time Frame: 3 years ]
- Tumor regression grade [ Time Frame: 1 year ]For rectal cancer patients who receive neoadjuvant treatment
- Overall survival [ Time Frame: 3 years ]
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03928652
|Contact: Ping Lan, PhDfirstname.lastname@example.org|
|The Sixth Affiliated Hospital, Sun Yet-sen University||Recruiting|
|Contact: Ping Lan, MD, PhD|