Physical Functions in Allogeneic-HSCT Candidates
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|ClinicalTrials.gov Identifier: NCT03915249|
Recruitment Status : Completed
First Posted : April 16, 2019
Last Update Posted : April 19, 2019
|Condition or disease|
|Stem Cell Transplantation|
|Study Type :||Observational|
|Actual Enrollment :||49 participants|
|Official Title:||Investigation of Relationship Among Physical Activity, Pulmonary Functions and Physical Functions in Candidates With Allogeneic Hematopoietic Stem Cell Transplantation: a Cross Sectional Study|
|Actual Study Start Date :||January 2017|
|Actual Primary Completion Date :||December 2018|
|Actual Study Completion Date :||February 2019|
Physical activity, pulmonary functions (FEV1, FVC, FEV1/FVC, FEF25-75%, PEF), exercise capacity, respiratory (maximal inspiratory and expiratory pressures (MIP, MEP)) and peripheral muscle strength were evaluated in allogeneic-HSCT candidates.
- Physical activity measurement [ Time Frame: during a total of 48 hours ]Physical activity levels of candidates were assessed with a metabolic holter device.
- Pulmonary function assessment [ Time Frame: 5 minutes ]It was evaluated using a spirometry by which is evaluated dynamic lung functions involving forced vital capacity (FVC), forced expiratory volume in one second (FEV1), forced expiratory volume in one second/forced vital capacity (FEV1/FVC), peak expiratory flow (PEF) and forced expiratory flow at 25%-75% (FEF25-75%). All of them are expressed as both liter (L) and percentages (%) of expected values. We used only percentages (%) of expected values for this study.
- inspiratory and expiratory muscle strength (MIP, MEP) [ Time Frame: 5-10 minutes ]Respiratory muscle strength was evaluated with a mouth pressure device
- Quadriceps femoris muscle strength [ Time Frame: 5 minutes ]Peripheral muscle strength was evaluated with a hand-held dynamometer
- Six-minute walk test [ Time Frame: 10 minutes ]Six-minute walk test was used to evaluate exercise capacity of candidates with reference to American Thoracic Society criteria.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03915249
|Study Chair:||Gülşah Barğı, PhD||Gazi Üniversitesi|
|Study Director:||Meral Boşnak Güçlü, PhD||Gazi Üniversitesi|
|Principal Investigator:||Gülsan Türköz Sucak, PhD.||Medikalpark hastanesi|