High School Football and Adult Health
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT03914573|
Recruitment Status : Completed
First Posted : April 16, 2019
Last Update Posted : April 18, 2019
|Condition or disease|
|Health Impairment Pain Obesity|
Data will be used from the Wisconsin Longitudinal Study (WLS), a long-term study of a random sample of 10,317 men and women who graduated from Wisconsin high schools in 1957 to determine the association between participation in high-school football and self-rated health, pain, and obesity in late adulthood. The WLS is an optimal observational dataset to answer these hypotheses. WLS captures early-life exposures that are important predictors of health and well-being in later life such parental socioeconomic status, occupation, and education level, family structure, and race. It also captures whether study participants participated in high school football and contains detailed measurements of their health in adulthood. WLS provides a robust and longitudinal dataset, overcoming the limitations of prior cross-sectional studies, to compare the health in later adulthood of those who played high school football to those who did not, after carefully controlling for a potential confounders
A matched observational study will be conducted, in which football players and controls will be divided into smaller subgroups which are relatively homogeneous along a range of baseline covariates. The outcomes will be compared within each matched set, after adjusting for residual imbalances in the distribution of these baseline covariates between the football players and controls.
|Study Type :||Observational|
|Actual Enrollment :||3355 participants|
|Official Title:||Observational Study of the Association of Participation in High School Football on Health in Late Adulthood|
|Actual Study Start Date :||January 1957|
|Actual Primary Completion Date :||December 2003|
|Actual Study Completion Date :||December 2011|
- Self-rated Health [ Time Frame: Collected in 2003-2005 when participants were aged 65 ]Subjects reported whether their health was excellent, very good, good, fair, or poor. We dichotomized subjects' responses, coding "excellent", "very good", and "good" as 0 and coding "fair" and "poor" as 1
- Pain that limits activities [ Time Frame: Collected in 2003-2005 when participants were aged 65 ]Subjects reported whether during the past 4 weeks, how many of their activities were limited by pain or discomfort. We coded subject responses as 1 if they responded that some, most, or all of their activities were limited and 0 if they responded that none or a few activities were limited.
- Difficulty in Activities of Daily Living [ Time Frame: Collected in 2003-2005 when participants were aged 65 ]Subjects reported whether during the past 4 weeks, have they been able to eat, bathe, dress and use the toilet without difficulty. We coded 0 for no difficulty and 1 for any difficulty.
- Maximum Lifetime Body Mass Index [ Time Frame: Collected in the WLS mail survey in 2004 ]Subjects reported their maximum lifetime weight and the age at which they weighed the most. From these responses, we computed the maximum adult BMI for each subject who reported that they reached their maximum weight when they were 18 years old or older.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03914573
|United States, Massachusetts|
|Massachusetts Institute of Technology|
|Cambridge, Massachusetts, United States, 02139|
|United States, Pennsylvania|
|University of Pennsylvania|
|Philadelphia, Pennsylvania, United States, 19104|
|Principal Investigator:||Timothy Gaulton, MD||University of Pennsylvania|
|Principal Investigator:||Sameer Deshpande, PhD||Massachusetts Insitute of Technology|
|Principal Investigator:||Dylan Small, PhD||University of Pennsylvania|
|Principal Investigator:||Mark D Neuman, MD||University of Pennsylvania|