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VR-assisted Curriculum on Depression for Stigma Reduction

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ClinicalTrials.gov Identifier: NCT03912597
Recruitment Status : Recruiting
First Posted : April 11, 2019
Last Update Posted : April 17, 2019
Sponsor:
Information provided by (Responsible Party):
Yale-NUS College

Brief Summary:
Two randomised controlled trials will be conducted to evaluate a virtual reality (VR) simulation designed to reduce stigma against depression. Qualitative interviews will also be carried out to evaluate the VR simulation.

Condition or disease Intervention/treatment Phase
Control Behavior Device: Virtual Reality Device: Brochure Device: Standard Video Control Not Applicable

Detailed Description:
The investigators examine the impact of a VR-assisted curriculum on stigma reduction towards individuals with depression. This is done through the development and evaluation of a VR-assisted curriculum that promotes stigma reduction towards depression among tertiary-aged students. Collection of data will provide insights about the effectiveness of VR's immersive quality in enhancing stigma reduction skills through measures of attitudes, beliefs and knowledge about depression. In the first study, VR is compared with traditional pamphlets in an information sharing booth about depression. In the second study, participants attend a 30-min session where they undergo an educational curriculum with either a VR or standard video as adjunctive tools.

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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 200 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Participant)
Primary Purpose: Other
Official Title: Reducing Stigma Against Depression: Designing and Implementing a VR-assisted Curriculum to Reduce Students' Perceptions of Patients With Depression
Actual Study Start Date : September 19, 2018
Estimated Primary Completion Date : April 20, 2019
Estimated Study Completion Date : April 20, 2019

Resource links provided by the National Library of Medicine


Arm Intervention/treatment
Experimental: Virtual Reality [A]
Participants watch a 4-minute virtual reality video, on top of reading a brochure, then answer post-intervention questionnaires.
Device: Virtual Reality
The 4-minute virtual reality video depicts a day in a life of a student with depression. The one-take video, filmed with a 360° camera, is designed to provide users with an immersive experience that simulates what it feels like to have depression. The user interface consisted of a Google Cardboard VR headset attached to a smartphone.

Device: Brochure
Participants read an informational brochure about depression depicting standard information about depression, including symptoms and information on how to support someone with depression.

Active Comparator: Brochure Waitlist Control [A]
Participants read an informational brochure about depression, then answer post-intervention questionnaires. After that, they will be given a chance to watch the VR video at the end of their participation session.
Device: Brochure
Participants read an informational brochure about depression depicting standard information about depression, including symptoms and information on how to support someone with depression.

Active Comparator: Standard Video Control [B]
Participants watch a 4-minute standard video. After which, using a video, a discussion of the video will be facilitated for participants to contextualise and understand the video better. Then, participants answer post-intervention questionnaires.
Device: Brochure
Participants read an informational brochure about depression depicting standard information about depression, including symptoms and information on how to support someone with depression.

Device: Standard Video Control
The 4-minute standard video depicts a similar storyline as was shown in the VR video. The standard video is filmed from a third-party perspective with multiple takes edited into a final video, following the standard filming style of these videos. The standard video will be viewed from a laptop with headphones attached.

Experimental: Virtual Reality [B]
Participants answer pre-questionnaires, then watch a 4-minute virtual reality video. After which, using a video, a discussion of the video will be facilitated for participants to contextualise and understand the video better. Then, participants answer post-intervention questionnaires.
Device: Virtual Reality
The 4-minute virtual reality video depicts a day in a life of a student with depression. The one-take video, filmed with a 360° camera, is designed to provide users with an immersive experience that simulates what it feels like to have depression. The user interface consisted of a Google Cardboard VR headset attached to a smartphone.

Device: Brochure
Participants read an informational brochure about depression depicting standard information about depression, including symptoms and information on how to support someone with depression.




Primary Outcome Measures :
  1. Stigmatising beliefs towards depression [ Time Frame: 2 minutes ]
    The extent of agreement with negative beliefs and stereotypes about depression will be adapted from the 10-item agreement sub-scale of the Self-Stigma of Mental Illness Scale.

  2. Stigmatising attitudes towards depression [ Time Frame: 5 minutes ]
    Stigmatising attitudes refer to the opinions that one has towards persons with depression, and how they would interact with these group of people. This will be measured using an adapted version of the Attribution Questionnaire-27.

  3. Knowledge about depression [ Time Frame: 2 minutes ]
    A Depression Literacy measure will be used to assess participants' understanding and knowledge of depression.

  4. Video Enjoyment [ Time Frame: 1 minute ]
    In the VR condition, enjoyment of the VR simulation will be assessed through five items on a video enjoyment questionnaire created by the researchers, that includes items such as "I found the video interesting" and "The video made me more interested in the topic" on a visual analog scale. The scale was anchored between 0 indicating "Strongly Disagree" to 10 indicating "Strongly Agree".

  5. Video Presence [ Time Frame: 1 minute ]
    Presence felt in the VR simulation will be assessed through four items on a video presence questionnaire, that includes items such as "How aware were you of events happening in your actual surroundings outside of the video?" and "How strong was your sense of 'being there' in the video environment?" on a visual analog scale. The questions were adapted from the original Presence Questionnaire by Witmer and Singer (1998) that outlined four sub-factors of control, sensory, distraction and realism; items in our questionnaire were carefully selected to represent all of the factors. The scale ranged from 0 indicating "Not At All" to 10 indicating "Very Much So".


Secondary Outcome Measures :
  1. Affect (PANAS) [ Time Frame: 3 minutes ]
    Participants' mood will be assessed using the Positive and Negative Affect Scale (PANAS) as a secondary measure of user experience with the respective videos. The PANAS consists of two 10-item subscales assessing positive and negative affect, and is rated on a 5-point scale ranging from 1 representing "Very Slightly or Not at All" to 5 representing "Extremely".

  2. Heart rate live tracking [ Time Frame: 4 minutes ]
    Changes in heart rate, assessed live during the video viewing duration, will be measured as a physiological measure of user experience.

  3. Qualitative feedback about VR video [ Time Frame: 10 minutes ]
    Participants will be invited to give feedback on their VR experience. Questions in the qualitative interview will address (1) their thoughts on mental health awareness amongst the public, (2) their experience watching the VR simulation and (3) reasons for stopping, or not, at similar mental health booths with VR simulations in the future.



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Ages Eligible for Study:   18 Years to 26 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Tertiary students from NUS and Yale-NUS only

Exclusion Criteria:

  • History of medical or psychiatric disorder; History of motion sickness, dizziness or epilepsy; (For reliability and safety of heart-rate monitoring) Tattoos near the wrist and/or nickel or acrylate allergies

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03912597


Contacts
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Contact: Jean Liu, PhD 66013694 jeanliu@yale-nus.edu.sg

Locations
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Singapore
Yale-NUS College Recruiting
Singapore, Singapore, 138527
Contact: Jean Liu, PhD       jeanliu@yale-nus.edu.sg   
Sponsors and Collaborators
Yale-NUS College

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Responsible Party: Yale-NUS College
ClinicalTrials.gov Identifier: NCT03912597     History of Changes
Other Study ID Numbers: S-18-208
First Posted: April 11, 2019    Key Record Dates
Last Update Posted: April 17, 2019
Last Verified: April 2019

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Yale-NUS College:
virtual reality
stigma reduction
depression
mental health campaigns
user experience
enjoyment
presence
Additional relevant MeSH terms:
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Depression
Behavioral Symptoms