Study on the Value of Three-dimensional Speckle Tracking Technique
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|ClinicalTrials.gov Identifier: NCT03905200|
Recruitment Status : Recruiting
First Posted : April 5, 2019
Last Update Posted : April 5, 2019
For a long time, it has been hoped that doctors could screen and diagnosis of coronary heart disease through non-invasive imaging techniques, so as to maximize the benefit/risk ratio of patients. This trial is to explore the screening and diagnostic value of three-dimensional speckle tracking technology for coronary heart disease, and the evaluation value of 3D speckle track image(3D-STI) technology for cardiac function improvement after coronary intervention, and to seek reliable, accurate and quantifiable non-invasive imaging examination for the diagnosis, follow-up and prognosis of coronary heart disease.
In this study, coronary angiography is taken as the "gold standard", and 3d-STI echocardiography technology is proposed to combine with clinical characteristics of subjects for joint diagnosis, so as to evaluate the value of 3d-sti technology in the diagnosis of coronary heart disease.
Patients were followed up with echocardiography after interventional treatment to explore the feasibility of 3D-STI technology in evaluating cardiac function improvement.
|Condition or disease||Intervention/treatment|
|Echocardiography, Three-Dimensional Coronary Artery Disease||Diagnostic Test: 3D-speckle tracking imaging|
|Study Type :||Observational|
|Estimated Enrollment :||800 participants|
|Official Title:||Study on the Value of Three-dimensional Speckle Tracking Technique in the Diagnosis and Follow-up of Coronary Heart Disease|
|Actual Study Start Date :||March 1, 2019|
|Estimated Primary Completion Date :||May 31, 2020|
|Estimated Study Completion Date :||December 31, 2020|
coronary artery disease
Patients who were diagnosed with coronary heart disease at admission and planned to undergo coronary angiography
Diagnostic Test: 3D-speckle tracking imaging
The strain peak value and strain peaking time of each segment (including 16 segments) of the left ventricular myocardium can be obtained by 3d-sti technology.
- Left ventricular myocardial viability [ Time Frame: half an hour ]
By measuring the strain and time to peak, the left ventricular myocardial viability was finally evaluated. Left ventricular local ventricular viable myocardium was quantitatively analyzed in patients .Aimed to detect the myocardial ischaemia and viability. The data of strain and time to peak were measured using the three-dimensional speckle tracking model.
In apical four-chamber view, make sure the endocardium, mitral valve ring and apex imaging is clear, mark the left and right mitral valve ring and apex spot . After automatic ultrasonic echo spot tracked, software can delineate endocardial curve, and automaticaly calculate the left ventricular myocardial segments strain and time to peak.
The strain peaks of each segment (including 16 segments) of the myocardium of the left ventricle included four strain peaks: RS, CS, LS and AS
- The value of 3D-STI technology on the improvement of left ventricular myocardial function [ Time Frame: half a year ]During the 6-month follow-up, 3D-STI technique was used to evaluate the improvement of left ventricular myocardial function compared with conventional parameters like LVEF and NYHA. 3D-STI parameters are the same : strain and peak time .
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03905200
|Beijing, Beijing, China, 100730|
|Contact: Xin Wang, Dotoral 86 10 58115037 firstname.lastname@example.org|