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Psychological Strengths and Burden Among Osteoarthritis Patient

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ClinicalTrials.gov Identifier: NCT03899272
Recruitment Status : Recruiting
First Posted : April 2, 2019
Last Update Posted : April 2, 2019
Sponsor:
Information provided by (Responsible Party):
Lawrence CM Lau, Chinese University of Hong Kong

Brief Summary:

Osteoarthritis (OA) is a common and debilitating disease, For the majority of patients, pain in OA is episodic in nature.

The experience of pain is generated or modified by nociception, neuropathic symptoms, psychological and personality factors, genetic influences, past painful experiences, comorbid conditions, and expectations related to future pain Previous studies have shown psychological well-being has been significantly associated with disability in patients with OA, and anxiety has been found to be associated with knee pain in women.

Previous studies also found that there are large interindividual differences among persons with knee osteoarthritis (OA) with respect to psychological function.

Psychological strengths and weaknesses are evaluated among new patient with osteoarthritis presented to joint replacement clinic, to facilitate our understanding of those patients need, and correlating with their radiological and clinical findings. Psychological strengths and weaknesses, positive and negative affects are evaluated in form of questionaires.

Reference:

Adaptation to disability: Applying selective optimization with compensation to the behaviors of older adults with osteoarthritis.

MAM Gignac, C Cott, EM Badley - Psychology and aging, 2002

Analgesic effects of multisensory illusions in osteoarthritis C Preston, R Newport - Rheumatology, 2011

Psychological factors and their relation to osteoarthritis pain BL Wise, J Niu, Y Zhang, N Wang, JM Jordan… - Osteoarthritis Cartilage. , 2010 - Elsevier


Condition or disease
Osteoarthritis, Knee Psychological

Detailed Description:

Introduction:

Osteoarthritis (OA) is a prevalent painful condition that may cause disability among older adults (Cruz-Almeida et al., 2013). Psychological traits and emotional states of patients were found to be correlated with symptoms of OA and daily functioning of patients (Cruz-Almeida et al., 2013; Dezutter et al., 2015).

The experience of pain is generated or modified by nociception, neuropathic symptoms, psychological and personality factors, genetic influences, past painful experiences, comorbid conditions, and expectations related to future pain. Previous studies have shown psychological well-being has been significantly associated with disability in patients with OA, and anxiety has been found to be associated with knee pain in women.

Previous studies also found that there are large interindividual differences among persons with knee osteoarthritis (OA) with respect to psychological function.

Aim of project:

This research is trying to find out what psychological strengths or factors could attenuate the chronic pain of knee OA patients. The purpose of the study is to find psychological evidences that may be used in the future to help chronic pain patients for improving their daily functioning and well-being.


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Study Type : Observational
Estimated Enrollment : 150 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Positive and Negative Affects Among Osteoarthritis Patient
Actual Study Start Date : June 1, 2018
Estimated Primary Completion Date : December 1, 2019
Estimated Study Completion Date : December 1, 2019

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Osteoarthritis

Group/Cohort
Osteoarthritis
All new patient present to clinic referred for osteoarthritis for considering joint replacement Present with knee pain (unilateral or bilateral) contributed by osteoarthritis



Primary Outcome Measures :
  1. Positive and Negative Affect Scale (PANAS) [ Time Frame: 1 day ]
    This scale consists of a number of questions that describe different feelings and emotions.

  2. The Centre for Epidemiologic Studies (CES-D Scale) [ Time Frame: 1 day ]
    A list of the ways the subject might have felt or behaved.

  3. The Chronic Pain Acceptance Questionnaire (CPAQ) [ Time Frame: 1 day ]
    Statements on feelings on pain as it applies to the subject.

  4. Chronic Pain Coping Inventory (CPCI-42) [ Time Frame: 1 day ]
  5. VIA-72 [ Time Frame: 1 day ]
    Questions reflect statements that the subject would find desirable.

  6. Kellgren & Lawrence (K & L) grading system [ Time Frame: 1 day ]
    To classify the severity of knee osteoarthritis (OA)

  7. Oxford knee scores [ Time Frame: 1 day ]
    Consists of 12 questions that cover function and pain of the knee.



Information from the National Library of Medicine

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Ages Eligible for Study:   65 Years and older   (Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

150 patients, based on previous studies (Psychological Profiles and Pain Characteristics of Older Adults With Knee Osteoarthritis; Psychological factors and their relation to osteoarthritis pain) and the number of patients and study time available in our clinic

Those are all the new patient present to AHNH clinic referred for osteoarthritis for considering joint replacement

Criteria

Inclusion Criteria:

  • all new patient present to AHNH clinic referred for osteoarthritis for considering joint replacement
  • Present with knee pain (unilateral or bilateral) contributed by osteoarthritis

Exclusion Criteria:

  • mentally unsound
  • dialectic speaker that difficult to communicate

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03899272


Contacts
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Contact: Lawrence Lau, Dr. 85235052211 lcm241@ha.org.hk

Locations
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Hong Kong
Alice Ho Miu Ling Nethersole Hospital Recruiting
Tai Po, Hong Kong
Contact: Lawrence Lau, Dr.    85235052211    lcm241@ha.org.hk   
Sponsors and Collaborators
Chinese University of Hong Kong

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Responsible Party: Lawrence CM Lau, Principal Investigator, Chinese University of Hong Kong
ClinicalTrials.gov Identifier: NCT03899272     History of Changes
Other Study ID Numbers: 2018.113
First Posted: April 2, 2019    Key Record Dates
Last Update Posted: April 2, 2019
Last Verified: March 2019
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No

Keywords provided by Lawrence CM Lau, Chinese University of Hong Kong:
osteoarthritis
psychology

Additional relevant MeSH terms:
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Osteoarthritis
Osteoarthritis, Knee
Arthritis
Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases