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Assessment of Intellectual Abilities for Subjects With Velopharyngeal Incompetence and Their Impact on Speech Intelligibility

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ClinicalTrials.gov Identifier: NCT03898713
Recruitment Status : Not yet recruiting
First Posted : April 2, 2019
Last Update Posted : July 3, 2019
Sponsor:
Information provided by (Responsible Party):
Zeinab Abdel Ghani Abdel Hameed Mohamed, Assiut University

Brief Summary:
To Assess effect of intelligence on speech production on subjects with velopharyngeal incompetence Search if there is any relation between congenital Velopharyngeal incompetence and decrease IQ of patients

Condition or disease Intervention/treatment
Velopharyngeal Incompetence Due to Cleft Palate Diagnostic Test: Intelligence quotient

Detailed Description:

Speech production is a complex process by which thoughts are generated into spoken utterances. Production involves the selection of appropriate words and the appropriate form of those words from the lexicon and morphology, and the organization of those words through the syntax. Then, the phonetic properties of the words are retrieved and the sentence is uttered through the articulations associated with those phonetic properties.

The term intelligibility refers to 'speech clarity' or the proportion of a speaker's output that a listener can readily understand.

Velopharyngeal Incompetence (VPI) refers to any situation in which an individual is unable to completely close the nasal airway during speech. The velopharyngeal mechanism is comprised of a complex group of structures that act in unison to control airflow through the nose and mouth by elevation of the soft palate and constriction of both the lateral and posterior pharyngeal walls. Any disruption in this mechanism may result in abnormal, poorly intelligible speech. VPI can manifest as hypernasality, nasal emission, decreased vocal intensity, and/or facial grimacing.

Intellectual ability refers to the skills required to think critically, see connections between disciplines and problem solve in new or changing situations. Memory, creative problem solving and vocabulary also contribute to the level of an individual's intellectual ability.

Orofacial clefts (OFCs) are frequently occurring human birth defects that have a complex, multifactorial etiology. Though structural orofacial defects are often surgically corrected during infancy and early childhood, OFC patient cohorts are at high risk for neurobehavioral problems including learning disability, impaired language function, psychosocial adjustment issues, and persistently reduced academic achievement.


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Study Type : Observational
Estimated Enrollment : 100 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Assessment of Intellectual Abilities for Subjects With Velopharyngeal Incompetence and Their Impact on Speech Intelligibility
Estimated Study Start Date : July 1, 2019
Estimated Primary Completion Date : July 1, 2020
Estimated Study Completion Date : July 1, 2020

Resource links provided by the National Library of Medicine



Intervention Details:
  • Diagnostic Test: Intelligence quotient
    intelligence quotient (IQ) is a total score derived from several standardized tests designed to assess human intelligence


Primary Outcome Measures :
  1. Auditory perceptual assessment [ Time Frame: Baseline ]
    Auditory-perceptual evaluation is the most commonly used clinical voice assessment method, and is often considered a gold standard for documentation of voice disorders.

  2. IQ test [ Time Frame: Baseline ]

    Assess IQ level of patients by standford binet version 4. An intelligence quotient (IQ) is a total score derived from several standardized tests designed to assess human intelligence.

    This is to search if there is any relation between IQ level and VPI and effect on speech intelligability




Information from the National Library of Medicine

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Ages Eligible for Study:   3 Years to 25 Years   (Child, Adult)
Sexes Eligible for Study:   All
Sampling Method:   Non-Probability Sample
Study Population
Patients will be collected randomly for one year from phoniatric department at Assiut university Hospital.
Criteria

Inclusion Criteria:

  • children with cleft lip and palate primary or secondary repaired
  • Velopharyngeal incompetence due to any cause especially short palate and deep pharynx
  • children above 3 years

Exclusion Criteria:

  • Hearing impairment
  • Neurological disease
  • ADHD

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03898713


Contacts
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Contact: Zeinab Soliman, Resident Dr. 01018119004 smile0smile@hotmail.com
Contact: Eman Abdel Haleem, Prof. Dr. 01064228598 emadkamelabdelhaleem@aun.edu.eg

Sponsors and Collaborators
Assiut University

Additional Information:
Publications:
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Responsible Party: Zeinab Abdel Ghani Abdel Hameed Mohamed, principle investigator at phoniatric department, Assiut University
ClinicalTrials.gov Identifier: NCT03898713     History of Changes
Other Study ID Numbers: IQ In VPI patients
First Posted: April 2, 2019    Key Record Dates
Last Update Posted: July 3, 2019
Last Verified: July 2019

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No

Keywords provided by Zeinab Abdel Ghani Abdel Hameed Mohamed, Assiut University:
IQ
Speech
VPI

Additional relevant MeSH terms:
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Cleft Palate
Velopharyngeal Insufficiency
Jaw Abnormalities
Jaw Diseases
Musculoskeletal Diseases
Maxillofacial Abnormalities
Craniofacial Abnormalities
Musculoskeletal Abnormalities
Stomatognathic Diseases
Mouth Abnormalities
Mouth Diseases
Stomatognathic System Abnormalities
Congenital Abnormalities
Pharyngeal Diseases
Otorhinolaryngologic Diseases