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Reliability of Chinese Version of Verbal Learning Test and Selective Reminding Test

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ClinicalTrials.gov Identifier: NCT03896308
Recruitment Status : Recruiting
First Posted : March 29, 2019
Last Update Posted : August 6, 2019
Sponsor:
Information provided by (Responsible Party):
Yea-Ru Yang, National Yang Ming University

Brief Summary:
Mild cognitive impairment (MCI) is distinguished from healthy aging by cognitive difficulties that are greater than expected for one's age and education. Amnestic mild cognitive impairment (aMCI) is a major sub-type of MCI with noticeable impairments in memory. Approximately 12% of aMCI will progress to AD per year. There are two test to evaluate the effects on memory, but both without Chinese version. This study is to know the test-retest reliability of the Chinese version of the Verbal learning test and Selective reminding test among people with mild cognitive impairment.

Condition or disease
Mild Cognitive Impairment Test-retest Reliability

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Study Type : Observational [Patient Registry]
Estimated Enrollment : 30 participants
Observational Model: Other
Time Perspective: Prospective
Target Follow-Up Duration: 2 Weeks
Official Title: Test-retest Reliability of the Chinese Version of the Verbal Learning Test and Selective Reminding Test Among People With Mild Cognitive Impairment
Actual Study Start Date : May 25, 2019
Estimated Primary Completion Date : February 28, 2020
Estimated Study Completion Date : March 19, 2020



Primary Outcome Measures :
  1. Chinese Version of Verbal Learning Test [ Time Frame: Change from baseline at two week ]
  2. Chinese Version of Selective Reminding Test [ Time Frame: Change from baseline at two week ]


Information from the National Library of Medicine

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Ages Eligible for Study:   50 Years to 100 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Mild cognitive impairment (MCI) is distinguished from healthy aging by cognitive difficulties that are greater than expected for one's age and education. Amnestic mild cognitive impairment (aMCI) is a major sub-type of MCI with noticeable impairments in memory. Approximately 12% of aMCI will progress to AD per year. Guidelines for MCI recommended: controlling vascular risk factors and focusing on behavioral interventions.
Criteria

Inclusion Criteria:

  1. Age≥50 years
  2. Complained of memory impairment
  3. Chinese Version Verbal Learning Test 10-minute delays ≤ 6 words
  4. MMSE score≥24 and CDR score=0.5
  5. Activities of daily living are intact
  6. DSM-IV criteria for the diagnosis of dementia is not met

Exclusion Criteria:

  1. Any significant neurologic disease other than suspected incipient Alzheimer's disease
  2. Psychotic features, contraindication of exercise... which could lead to difficulty complying with the protocol

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03896308


Locations
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Taiwan
National Yang-Ming University Recruiting
Taipei, Taiwan
Contact: Yea-Ru Yang, PhD    886-2-28267279    yryang@ym.edu.tw   
Sponsors and Collaborators
National Yang Ming University

Additional Information:

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Responsible Party: Yea-Ru Yang, Professor, National Yang Ming University
ClinicalTrials.gov Identifier: NCT03896308     History of Changes
Other Study ID Numbers: YM108036E
First Posted: March 29, 2019    Key Record Dates
Last Update Posted: August 6, 2019
Last Verified: August 2019

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Additional relevant MeSH terms:
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Cognitive Dysfunction
Cognition Disorders
Neurocognitive Disorders
Mental Disorders