Strengthening Effect on Hamstring's Passive Mechanical Properties

• ClinicalTrials.gov Identifier: NCT03884738
• Recruitment Status: Completed
• First Posted: March 21, 2019
• Last Update Posted: April 22, 2020
• Sponsor: Hacettepe University
• Information provided by (Responsible Party): Özgün Uysal, Hacettepe University

Study Description

Brief Summary:

The purpose of this study was to investigate effects of different strengthening methods on hamstring muscle group's passive mechanical properties and to investigate this effect's relation with performance changes in healthy individuals. 42 healthy sedentary male participated in this study. Passive mechanical properties and strength of hamstring and quadriceps muscles, flexibility of hamstring muscles, anaerobic explosive strength, reaction time, agility were measured. Participants randomized evenly into one of three groups; eccentric, concentric and neuromuscular electrical stimulation (NMES). After 8 weeks training period, participants were measured again.

Condition or disease	Intervention/treatment	Phase
Sports Physical Therapy	Other: Concentric Exercise; Other: Nordic Eccentric exercise; Other: Neuromuscular Electrical Stimulation	Not Applicable

Study Design

• Study Type: Interventional (Clinical Trial)
• Actual Enrollment: 42 participants
• Allocation: Randomized
• Intervention Model: Parallel Assignment
• Intervention Model Description: randomization into three groups and measurement before and after intervention
• Masking: None (Open Label)
• Primary Purpose: Basic Science
• Official Title: Effects Of Different Strengthening Methods On Hamstring Muscle Group's Passive Mechanical Properties in Healthy Individuals
• Actual Study Start Date: March 21, 2019
• Actual Primary Completion Date: December 1, 2019
• Actual Study Completion Date: December 1, 2019

Arms and Interventions

Arm	Intervention/treatment
Active Comparator: Concentric; Leg Curl Training	Other: Concentric Exercise; Leg Curl Machine: 1st week - 1st day is 10 maximum repeat test. 2nd week - 2 days of training - 2 sets of 6 repeats. %60 percent of maximum load. 3rd week - 3 days of training - 3 sets of 6-8 repeats. %60-80 of maximum load. 4th-8th week - 3 days of training - 3 sets of 8-12 repeats. when 3 sets of 12 achieved, load was increased with 2.5kg.
Active Comparator: Eccentric; Nordic Hamstring Training	Other: Nordic Eccentric exercise; st week - 1 day - 2 sets of 5 repeats.; nd week - 2 days - 2 sets of 6 repeats.; rd week - 3 days - 3 sets of 6-8 repeats.; th week - 3 days - 3 sets of 8-10 repeats. 5-8th weeks - 3 days - 3 sets of 12-8 repeats. When achieved 3 sets of 12 repeats with full range, speed was increased.
Active Comparator: Neuromuscular Electrical Stimulation; Stimulation Training	Other: Neuromuscular Electrical Stimulation; 8 weeks, three times per week, 15 minutes of bilateral hamstring stimulation. 100 Hz. frequency, 600 microsecond duration rectangular current

Outcome Measures

Primary Outcome Measures :

1. Passive Mechanical Properties [ Time Frame: Change from baseline passive mechanical properties at 8 weeks ]
   Tone, Elasticity and Stiffness evaluation. Evaluated with Myotonometer-3

Secondary Outcome Measures :

1. Flexibility Measurement [ Time Frame: Change from baseline flexibility at 8 weeks ]
   Sit and reach test was used for hamstring flexibility
2. Muscle Strength Measurement [ Time Frame: Change from baseline muscle strength at 8 weeks ]
   Hamstring and Quadriceps strength were measured with LaFayette Manuel Muscle Tester
3. Agility Measurement [ Time Frame: Change from baseline agility time at 8 weeks ]
   Illinois Agility Test was used for agility measurement
4. Anaerobic Explosive Power [ Time Frame: Change from baseline anaerobic explosive power at 8 weeks ]
   Jump and Reach test was administered
5. Reaction Time [ Time Frame: Change from baseline reaction time at 8 weeks ]
   ruler drop test was used for reaction timing

Eligibility Criteria

• Ages Eligible for Study: 18 Years to 30 Years (Adult)
• Sexes Eligible for Study: Male
• Gender Based Eligibility: Yes
• Gender Eligibility Description: only male participants were accepted
• Accepts Healthy Volunteers: Yes

Criteria

Inclusion Criteria:

• being sedentary

Exclusion Criteria:

• Having knee, hip and/or back pain
• Having a cardiovascular condition/disease
• History of previous knee and/or hip surgery
• Having a diagnose of any systemic disease
• History of previous hamstring injury
• Being physically active within last year ( Regular activity at least 3 days a week and continuity of at least 2 months was accepted as being physically active)

Contacts and Locations

Locations

Turkey

Hacettepe University

Ankara, Turkey, 06100

Sponsors and Collaborators

Hacettepe University

Investigators

• Study Director: tuzun fırat, Assoc. Prof.; Hacettepe University

More Information

Publications:

Ayala F, Sainz de Baranda P, De Ste Croix M, Santonja F. Reproducibility and criterion-related validity of the sit and reach test and toe touch test for estimating hamstring flexibility in recreationally active young adults. Phys Ther Sport. 2012 Nov;13(4):219-26. doi: 10.1016/j.ptsp.2011.11.001. Epub 2012 Jan 23.

Mentiplay BF, Perraton LG, Bower KJ, Adair B, Pua YH, Williams GP, McGaw R, Clark RA. Assessment of Lower Limb Muscle Strength and Power Using Hand-Held and Fixed Dynamometry: A Reliability and Validity Study. PLoS One. 2015 Oct 28;10(10):e0140822. doi: 10.1371/journal.pone.0140822. eCollection 2015.

Amiri-Khorasani M, Sahebozamani M, Tabrizi KG, Yusof AB. Acute effect of different stretching methods on Illinois agility test in soccer players. J Strength Cond Res. 2010 Oct;24(10):2698-704. doi: 10.1519/JSC.0b013e3181bf049c.

Schwesig R, Koke A, Fischer D, Fieseler G, Jungermann P, Delank KS, Hermassi S. Validity and Reliability of the New Handball-Specific Complex Test. J Strength Cond Res. 2016 Feb;30(2):476-86. doi: 10.1519/JSC.0000000000001061.

Mjølsnes R, Arnason A, Østhagen T, Raastad T, Bahr R. A 10-week randomized trial comparing eccentric vs. concentric hamstring strength training in well-trained soccer players. Scand J Med Sci Sports. 2004 Oct;14(5):311-7.

Glaviano NR, Langston WT, Hart JM, Saliba S. Influence of patterned electrical neuromuscular stimulation on quadriceps activation in individuals with knee joint injury. Int J Sports Phys Ther. 2014 Dec;9(7):915-23.

• Responsible Party: Özgün Uysal, Research Assistant, Hacettepe University
• ClinicalTrials.gov Identifier: NCT03884738
• Other Study ID Numbers: HacettepeSportsPhysio
• First Posted: March 21, 2019
• Last Update Posted: April 22, 2020
• Last Verified: April 2020

Individual Participant Data (IPD) Sharing Statement:

• Plan to Share IPD: No

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No

Keywords provided by Özgün Uysal, Hacettepe University:

Muscle Tonus; Elasticity; Electric Stimulation Therapy; Physical Conditioning, Human