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Strengthening Effect on Hamstring's Passive Mechanical Properties

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT03884738
Recruitment Status : Completed
First Posted : March 21, 2019
Last Update Posted : April 22, 2020
Information provided by (Responsible Party):
Özgün Uysal, Hacettepe University

Brief Summary:
The purpose of this study was to investigate effects of different strengthening methods on hamstring muscle group's passive mechanical properties and to investigate this effect's relation with performance changes in healthy individuals. 42 healthy sedentary male participated in this study. Passive mechanical properties and strength of hamstring and quadriceps muscles, flexibility of hamstring muscles, anaerobic explosive strength, reaction time, agility were measured. Participants randomized evenly into one of three groups; eccentric, concentric and neuromuscular electrical stimulation (NMES). After 8 weeks training period, participants were measured again.

Condition or disease Intervention/treatment Phase
Sports Physical Therapy Other: Concentric Exercise Other: Nordic Eccentric exercise Other: Neuromuscular Electrical Stimulation Not Applicable

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 42 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Intervention Model Description: randomization into three groups and measurement before and after intervention
Masking: None (Open Label)
Primary Purpose: Basic Science
Official Title: Effects Of Different Strengthening Methods On Hamstring Muscle Group's Passive Mechanical Properties in Healthy Individuals
Actual Study Start Date : March 21, 2019
Actual Primary Completion Date : December 1, 2019
Actual Study Completion Date : December 1, 2019

Arm Intervention/treatment
Active Comparator: Concentric
Leg Curl Training
Other: Concentric Exercise

Leg Curl Machine: 1st week - 1st day is 10 maximum repeat test. 2nd week - 2 days of training - 2 sets of 6 repeats. %60 percent of maximum load.

3rd week - 3 days of training - 3 sets of 6-8 repeats. %60-80 of maximum load. 4th-8th week - 3 days of training - 3 sets of 8-12 repeats. when 3 sets of 12 achieved, load was increased with 2.5kg.

Active Comparator: Eccentric
Nordic Hamstring Training
Other: Nordic Eccentric exercise
  1. st week - 1 day - 2 sets of 5 repeats.
  2. nd week - 2 days - 2 sets of 6 repeats.
  3. rd week - 3 days - 3 sets of 6-8 repeats.
  4. th week - 3 days - 3 sets of 8-10 repeats. 5-8th weeks - 3 days - 3 sets of 12-8 repeats. When achieved 3 sets of 12 repeats with full range, speed was increased.

Active Comparator: Neuromuscular Electrical Stimulation
Stimulation Training
Other: Neuromuscular Electrical Stimulation
8 weeks, three times per week, 15 minutes of bilateral hamstring stimulation. 100 Hz. frequency, 600 microsecond duration rectangular current

Primary Outcome Measures :
  1. Passive Mechanical Properties [ Time Frame: Change from baseline passive mechanical properties at 8 weeks ]
    Tone, Elasticity and Stiffness evaluation. Evaluated with Myotonometer-3

Secondary Outcome Measures :
  1. Flexibility Measurement [ Time Frame: Change from baseline flexibility at 8 weeks ]
    Sit and reach test was used for hamstring flexibility

  2. Muscle Strength Measurement [ Time Frame: Change from baseline muscle strength at 8 weeks ]
    Hamstring and Quadriceps strength were measured with LaFayette Manuel Muscle Tester

  3. Agility Measurement [ Time Frame: Change from baseline agility time at 8 weeks ]
    Illinois Agility Test was used for agility measurement

  4. Anaerobic Explosive Power [ Time Frame: Change from baseline anaerobic explosive power at 8 weeks ]
    Jump and Reach test was administered

  5. Reaction Time [ Time Frame: Change from baseline reaction time at 8 weeks ]
    ruler drop test was used for reaction timing

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   18 Years to 30 Years   (Adult)
Sexes Eligible for Study:   Male
Gender Based Eligibility:   Yes
Gender Eligibility Description:   only male participants were accepted
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • being sedentary

Exclusion Criteria:

  • Having knee, hip and/or back pain
  • Having a cardiovascular condition/disease
  • History of previous knee and/or hip surgery
  • Having a diagnose of any systemic disease
  • History of previous hamstring injury
  • Being physically active within last year ( Regular activity at least 3 days a week and continuity of at least 2 months was accepted as being physically active)

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT03884738

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Hacettepe University
Ankara, Turkey, 06100
Sponsors and Collaborators
Hacettepe University
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Study Director: tuzun fırat, Assoc. Prof. Hacettepe University

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Responsible Party: Özgün Uysal, Research Assistant, Hacettepe University Identifier: NCT03884738    
Other Study ID Numbers: HacettepeSportsPhysio
First Posted: March 21, 2019    Key Record Dates
Last Update Posted: April 22, 2020
Last Verified: April 2020
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Özgün Uysal, Hacettepe University:
Muscle Tonus
Electric Stimulation Therapy
Physical Conditioning, Human