Placental Insufficiency Microcirculation Quantification by Ultrafast Doppler (MICRODOPPLER PLACENTA)
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|ClinicalTrials.gov Identifier: NCT03860103|
Recruitment Status : Recruiting
First Posted : March 1, 2019
Last Update Posted : April 16, 2019
To identify fetuses small for their gestational-age who have reached their appropriate growth potential from growth-restricted fetuses due to placental insufficiency is uneasy. Intra Uterine Growth Restriction (IUGR) increases the risk for indicated preterm delivery, neonatal mortality and morbidity. Therefore, improving the knowledge of the placental perfusion is essential to better identify and manage fetal chronic oxygen deprivation associated with placental insufficiency. Thus, the investigators propose to study placental microcirculation with a more efficient Doppler than conventional Doppler use in clinical practice. The Ultrafast Doppler is being able to map placental blood flow and could have potential impact in placental insufficiency diagnosis and prevention. Moreover, this Doppler could discriminate maternal and fetal vascularization.
The hypothesis is that Ultrafast Doppler could help clinician to diagnose and manage preeclampsia and IUGR during pregnancy.
|Condition or disease|
|Preeclampsia and Intrauterine Growth Restriction|
|Study Type :||Observational|
|Estimated Enrollment :||165 participants|
|Official Title:||Placental Insufficiency Microcirculation Quantification by Ultrafast Doppler: an Observational Prospective Study|
|Actual Study Start Date :||March 12, 2019|
|Estimated Primary Completion Date :||November 30, 2019|
|Estimated Study Completion Date :||June 30, 2020|
- Qualitative analysis (velocities) of intraplacental blood flow after acquisition of sequences in Ultrafast Doppler imaging [ Time Frame: from the 12 week of gestation ]
- Quantitative analysis (flow rates) of intraplacental blood flow after acquisition of sequences in Ultrafast Doppler [ Time Frame: from the 12 week of gestation ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03860103
|Contact: Chloé Arthuis, Dremail@example.com|
|Nantes University Hospital||Recruiting|
|Nantes, France, 44093|
|Contact: Chloë Arthuis, PH firstname.lastname@example.org|