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3DV+TPS Software Outlines the Radiotherapy of Nasopharyngeal Carcinoma

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT03810274
Recruitment Status : Completed
First Posted : January 18, 2019
Last Update Posted : January 18, 2019
Information provided by (Responsible Party):
Jianguo Sun, Xinqiao Hospital of Chongqing

Brief Summary:
Comparing the accuracy and speed of 3DV+TPS software with imported TPS and domestic TPS to outline the contours of crisis organs, it is proved that 3DV+TPS has superiority compared with domestic TPS, and it has non-inferiority compared with imported TPS, indicating that the software can improve contour sketching accuracy. And speed, reduce the burden on doctors, improve medical efficiency.

Condition or disease Intervention/treatment
Radiotherapy Nasopharyngeal Carcinoma Device: 3DV+TPS;VARIAN TPS;FonicsPlan

Detailed Description:
Comparing the accuracy and speed difference between 3DV+TPS software and imported TPS and domestic TPS to outline the contours of crisis organs, the selected organs are: bilateral eyeballs, bilateral crystals, bilateral optic nerves, bilateral parotid glands, oral cavity, spinal cord, brainstem, The brain has a total of 12 organs; verify that 3DV+TPS is superior to domestic TPS, and has non-inferiority compared with imported TPS, Ming software can improve the accuracy and speed of contour sketching, reduce the burden on doctors, and improve medical efficiency.

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Study Type : Observational
Actual Enrollment : 300 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: 3DV+TPS Software Outlines the Outline of Radiotherapy for Nasopharyngeal Carcinoma Center Comparison Study Clinical Research
Actual Study Start Date : February 1, 2012
Actual Primary Completion Date : December 31, 2018
Actual Study Completion Date : January 15, 2019

Resource links provided by the National Library of Medicine

Group/Cohort Intervention/treatment
This experiment included a total of 300 patients with nasopharyngeal carcinoma, using 3DV + TPS software and imported TPS, domestic TPS, these three sets of TPS delineate bilateral crystal, bilateral optic nerve, bilateral eyeball, bilateral parotid gland, oral cavity, spinal cord There are 12 organs in the brainstem and brain, and the accuracy and speed of the 3 sets of TPS sketches are compared.
Device: 3DV+TPS;VARIAN TPS;FonicsPlan

Primary Outcome Measures :
  1. Sketching accuracy [ Time Frame: one year ]
    Define ΔV as a percentage of the total volume of the gold standard;

  2. Sketch speed [ Time Frame: one year ]
    Use the stopwatch to record the total time used to draw down 12 organs, to start sketching as the starting point of the time, and to finish the saving of the data.

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 70 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
A total of 7 different grade hospital radiotherapy centers have received radiotherapy for patients with nasopharyngeal carcinoma Case information, based on inclusion and exclusion criteria, a total of 300 cases were screened. Among them, Xinqiao Hospital collected 180 cases, He collected 20 cases in 20 hospitals, totaling 200 cases.

Inclusion Criteria:

  1. It is diagnosed as nasopharyngeal carcinoma by histopathological examination, and there is no tumor invasion in the organs that need to be assessed;
  2. Age 18-70 years old;
  3. There is nasopharynx localization enhanced CT, nasopharynx enhanced MRI.

Exclusion Criteria:

  1. Patient information is incomplete; no age, gender, MRI, height, radiotherapy location CT;
  2. The organs at risk that need to be assessed are invaded by the tumor;
  3. Any reason cannot be combined with the research or the researcher believes that it is not suitable for inclusion in this test.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT03810274

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Xinqiao Hospital of Chongqing
Chongqing, China, 400000
Sponsors and Collaborators
Xinqiao Hospital of Chongqing

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Responsible Party: Jianguo Sun, Deputy Director, Xinqiao Hospital of Chongqing Identifier: NCT03810274     History of Changes
Other Study ID Numbers: XQonc-012
First Posted: January 18, 2019    Key Record Dates
Last Update Posted: January 18, 2019
Last Verified: January 2019

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Additional relevant MeSH terms:
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Nasopharyngeal Carcinoma
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Nasopharyngeal Neoplasms
Pharyngeal Neoplasms
Otorhinolaryngologic Neoplasms
Head and Neck Neoplasms
Neoplasms by Site
Nasopharyngeal Diseases
Pharyngeal Diseases
Stomatognathic Diseases
Otorhinolaryngologic Diseases