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TransIent Perivascular Inflammation of the Carotid Artery (TIPIC) Syndrome: Clinical and Radiological Follow-up (TIPIC-UNV)

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ClinicalTrials.gov Identifier: NCT03804112
Recruitment Status : Recruiting
First Posted : January 15, 2019
Last Update Posted : January 16, 2019
Sponsor:
Information provided by (Responsible Party):
Fondation Ophtalmologique Adolphe de Rothschild

Brief Summary:
TIPIC syndrome (previously called carotidynia) is a rare entity of unknown cause, where the patient has a temporary cervical pain associated with a suggestive inflammation around the carotid artery. Usually considered as a unique and benign episode, some patients have recurrences and the follow-up is usually short. In this study the investigators aim to evaluate patients who presented a TIPIC episode at least 3 months before, clinically and with a cervical doppler ultrasound

Condition or disease Intervention/treatment
Cervical Pain Vasculitis Diagnostic Test: Ultrasound exam with Doppler Biological: Blood samples

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Study Type : Observational
Estimated Enrollment : 47 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: TransIent Perivascular Inflammation of the Carotid Artery (TIPIC) Syndrome: Clinical and Radiological Follow-up
Actual Study Start Date : December 17, 2018
Estimated Primary Completion Date : June 2019
Estimated Study Completion Date : July 2019

Intervention Details:
  • Diagnostic Test: Ultrasound exam with Doppler
    Ultrasound exam of the neck to search a perivascular inflammation at the level of the carotid bifurcation.
  • Biological: Blood samples
    blood count , CRP and viral serologies (herpes virus, chlamydia, mycoplasma),


Primary Outcome Measures :
  1. Assess the incidence of recurrence of TIPIC syndrome after a first episode [ Time Frame: 1 year ]


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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
all patient previously identified with a TIPC syndrom
Criteria

Inclusion Criteria:

- Patients with at least one episode of TIPIC syndrome for more than 12 months


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03804112


Contacts
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Contact: Laurence SALOMON, MD PhD 0148036431 ext +33 lsalomon@for.paris
Contact: Michael Obadia, MD mobadia@for.paris

Locations
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France
CHU de Montpellier Not yet recruiting
Montpellier, France, 34295
Contact: Nicolas MENJOT DE CHAMPLEUR, MD       nicolasdechampfleur@orange.fr   
Hôpital Pitié Salpêtrière Not yet recruiting
Paris, France, 75013
Contact: Mélika AMOR-SAHLI    0142163512    melikasahli81@gmail.com   
Centre Hospitalier de Saint-Anne Not yet recruiting
Paris, France, 75014
Contact: Olivier NAGGARA       O.naggara@ch-sainte-anne.fr   
Fondation Ophtalmologique A. de Rothschild Recruiting
Paris, France, 75019
Contact: Michael OBADIA, MD       mobadia@for.paris   
CHU de Toulouse Not yet recruiting
Toulouse, France, 31059
Contact: Nathalie NASR, MD    0561775602    nasr.n@chu-toulouse.fr   
CHU de TOURS Not yet recruiting
Tours, France, 37044
Contact: Marie GAUDRON, MD    02.47.47.47.47    m.gaudron@chu-tours.fr   
Sponsors and Collaborators
Fondation Ophtalmologique Adolphe de Rothschild

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Responsible Party: Fondation Ophtalmologique Adolphe de Rothschild
ClinicalTrials.gov Identifier: NCT03804112     History of Changes
Other Study ID Numbers: MOA_2018_2
First Posted: January 15, 2019    Key Record Dates
Last Update Posted: January 16, 2019
Last Verified: January 2019

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No

Additional relevant MeSH terms:
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Inflammation
Vasculitis
Neck Pain
Pathologic Processes
Vascular Diseases
Cardiovascular Diseases
Pain
Neurologic Manifestations
Signs and Symptoms