Delta Shock Index in Predicting Massive Transfusion
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|ClinicalTrials.gov Identifier: NCT03786705|
Recruitment Status : Completed
First Posted : December 25, 2018
Last Update Posted : December 25, 2018
Background: To determine the performance of delta shock index (ΔSI), a change in shock index (SI) upon arrival at the emergency room (ER) from that in the field in predicting the need for massive transfusion (MT) among adult trauma patients with stable blood pressure.
Methods: This study included data from all trauma patients aged 20 years and above who were hospitalized from January 1, 2009 to December 31, 2016 and was obtained from the registered trauma database of the hospital. Only patients who were transferred by emergency medical service from the accident site with a systolic blood pressure ≥ 90 mm Hg at the ER were included in this study. The 7,957 enrolled trauma patients were divided into 2 groups, those who had received blood transfusion ≥ 10 U (MT, n = 82) and those who had not (non-MT, n = 7,875). The odds ratios with 95% confidence intervals for associated patient conditions and the odds of need for MT by a given ΔSI were measured. The plot of specific receiver operating characteristic (ROC) curves was used to evaluate the best cutoff point that could predict the patient's probability of receiving MT.
|Condition or disease||Intervention/treatment|
|Trauma Patients Received Blood Transfusion ≥ 10 U Trauma Patients Had Not Received Blood Transfusion ≥ 10 U||Other: Massive transfusion Other: Non-Massive Transfusion|
|Study Type :||Observational|
|Actual Enrollment :||7957 participants|
|Official Title:||The Relationship of Delta Shock Index With the Requirement of Blood Transfusion and Clinical Outcome of Adult Trauma Patients|
|Actual Study Start Date :||June 5, 2018|
|Actual Primary Completion Date :||December 20, 2018|
|Actual Study Completion Date :||December 20, 2018|
Trauma patients' SBP ≥ 90 mm Hg with EMS
Only patients who were transferred by emergency medical service from the accident site with a systolic blood pressure ≥ 90 mm Hg at the ER were included in this study. The enrolled trauma patients divided into 2 groups, those who had received blood transfusion ≥ 10 U (massive transfusion) and those who had not (non-massive transfusion).
Other: Massive transfusion
Trauma patients who had received blood transfusion≥10 U
Other: Non-Massive Transfusion
Trauma patients who had received blood transfusion<10 U
- in-hospital mortality [ Time Frame: up to 5 months ]To measure the outcome of patients.
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Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03786705
|Kaohsiung Chang Gung Memorial Hospital|
|Kaohsiung, Taiwan, 83301|