A Comparative Study of Brain Structure and Amyloid Load in MCI Patients
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|ClinicalTrials.gov Identifier: NCT03773185|
Recruitment Status : Suspended (Low recruitment rate)
First Posted : December 12, 2018
Last Update Posted : January 27, 2021
Older people with DM are at greater risk of cognitive decline than their counterparts with DM. Cognitive impairment in older people with DM may be associated with non-AD related brain atrophy and white matter disease. The investigators therefore propose to compare DM and non-DM older people with amnesic MCI in brian volumes, white matter disease and amyloid load.
30 older people with aMCI, 30 older people with aMCI and DM, age 65-85 will be recruited. They all will have amyloid PET scan and MRI brain scan.
|Condition or disease|
|Mild Cognitive Impairment|
|Study Type :||Observational [Patient Registry]|
|Estimated Enrollment :||60 participants|
|Target Follow-Up Duration:||1 Month|
|Official Title:||A Comparative Study of Brain Structure and Amyloid Load Between Cognitively Impaired Older People With or Without Diabetes Mellitus|
|Actual Study Start Date :||December 15, 2018|
|Actual Primary Completion Date :||October 31, 2020|
|Estimated Study Completion Date :||October 31, 2021|
- Amyloid load [ Time Frame: Two years ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03773185
|The Chinese University of Hong Kong|
|Hong Kong, Hong Kong|
|Principal Investigator:||Timothy Kwok, MD||Chinese University of Hong Kong|