Pharmacogenetics for Pain Management in Joint Replacement Patients (PGx)
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|ClinicalTrials.gov Identifier: NCT03772535|
Recruitment Status : Enrolling by invitation
First Posted : December 11, 2018
Last Update Posted : August 1, 2019
|Condition or disease||Intervention/treatment||Phase|
|Arthroplasty Complications||Diagnostic Test: Pharmacogenomics Testing||Phase 3|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||50 participants|
|Intervention Model:||Crossover Assignment|
|Official Title:||Using Pharmacogenetics to Structure Individual Pain Management Protocols for Joint Replacement Patients|
|Actual Study Start Date :||December 3, 2018|
|Estimated Primary Completion Date :||June 2020|
|Estimated Study Completion Date :||December 2020|
No Intervention: Control Group
Subjects in this arm will receive the standard postoperative pain prescription protocol.
Active Comparator: Pharmacogenomics Guided Group
Subjects in this group will receive postoperative pain prescriptions based on the results of pharmacogenomic testing.
Diagnostic Test: Pharmacogenomics Testing
The doctor will use genetic test results to prescribe medications that are a most effective for subject.
- Genetic variants [ Time Frame: 10 days postoperative ]Percent of subject with genetic variants affecting pain medication
- pain levels [ Time Frame: 10 days postoperatively ]0-10 subjective pain scale
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03772535
|United States, Virginia|
|Anderson Orthopaedic Research Institute|
|Alexandria, Virginia, United States, 22307|
|Principal Investigator:||William Hamilton, MD||Anderson Orthopaedic Research Institute|