Ventilatory Monitoring in Children With Respiratory Distress Syndrome With Electrical Impedance Tomography
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|ClinicalTrials.gov Identifier: NCT03768921|
Recruitment Status : Recruiting
First Posted : December 7, 2018
Last Update Posted : December 7, 2018
|Condition or disease||Intervention/treatment||Phase|
|Respiratory Distress Syndrome||Other: PEEP Titriation||Not Applicable|
Show Detailed Description
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||20 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Masking Description:||The research design is a longitudinal, quantitative and analytical clinical trial.|
|Primary Purpose:||Supportive Care|
|Official Title:||Use of Electrical Impedance Tomography in Children With Syndrome of Acute Respiratory Disorder|
|Actual Study Start Date :||January 10, 2018|
|Estimated Primary Completion Date :||December 31, 2019|
|Estimated Study Completion Date :||December 31, 2019|
Experimental: PEEP Titriation
patients with respiratory distress syndrome will undergo alveolar recruitment in the mechanical ventilator and will have their final positive mechanical ventilator pressure determined by ventilator evaluation by the electrical impedance tomograph. The increase of the peep in the mechanical ventilator to perform the alveolar recruitment will be of 2 in 2 cmH2O every 2 minutes until the pressure reaches 25 cmH20, after the pressure was reduced in the same way being evaluated in the tomograph what will be the point with greater alveolar recruitment, having greater ventilation, without alveolar hyperdistension or alveolar collapse.
Other: PEEP Titriation
The alveolar recruitment maneuver PEEP reaches a maximum of 25 cmH2O, with recruitment being performed progressively, where the pressure variation is maintained at 15 cmH2O and the PEEP increase progressively occurs at 2 cmH2O every 2 minutes and Ventilatory mode with Controlled Pressure Ventilation. After the alveolar recruitment maneuver, the PEEP titration or determination will be performed, where the PEEP of 2 cmH2O will be reduced every 2 minutes and the variables after the alveolar recruitment maneuver and PEEP maintenance will be checked in the TIMPEL brand equipment at the point where the patient has better alveolar recruitment, with fewer alveolar collapsing points and pulmonary hyperdistension.
- Driving pressure [ Time Frame: evaluation during two days ]The driving pressure, which indicates alveolar pressure variation and alveolar distension capacity, will be evaluated.
- Alveolar collapse [ Time Frame: evaluation during two days ]the percentage of alveolar collapse, which indicates how much the pulmonary alveolus is without air.
- Alveolar hiperdistension [ Time Frame: Evaluation during two days ]the percentage of hyperdistended alveoli, which indicates that the alveoli are with excess air in their interior.
- Regional air ventilation [ Time Frame: Evaluation during two days ]Regional air ventilation, which indicates how air is distributed in the lung, demonstrating the most ventilated and least ventilated areas in the lung.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03768921
|Fundação Santa Casa de Misericórdia do Pará||Recruiting|
|Belém, Pará, Brazil, 66.050-380|
|Contact: Paulo E Avila, Doctor +55 91 981291251 firstname.lastname@example.org|
|Principal Investigator:||Rodrigo S Rocha, Phd||Universidade do Estado do Pará|