Diastolic Dysfunction and Interstitial Lung Edema in Septic Patients
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT03768752|
Recruitment Status : Recruiting
First Posted : December 7, 2018
Last Update Posted : February 4, 2019
|Condition or disease|
|Sepsis Diastolic Dysfunction Lung Edema Fluid Overload|
|Study Type :||Observational|
|Estimated Enrollment :||50 participants|
|Official Title:||Left Ventricular Diastolic Dysfunction as a Risk Factor for Interstitial Lung Edema and General Edema in Septic Patients on the Intensive Care Unit|
|Actual Study Start Date :||October 11, 2018|
|Estimated Primary Completion Date :||August 1, 2019|
|Estimated Study Completion Date :||September 1, 2019|
Patients with pre-existing or new diastolic dysfunction.
Normal Diastolic Function
Patients with normal diastolic function.
- Diastolic Dysfunction [ Time Frame: While in septic condition, up to 10 days maximum. ]Diastolic Dysfunction specified by echocardiographic doppler derived mitral inflow pattern and tissue doppler derived diastolic mitral annular velocities (E/E').
- Pulmonary Edema [ Time Frame: While in septic condition, up to 10 days maximum. ]Pulmonary edema specified by B line ultrasound score (Lung ultrasound protocol for the assessment of pulmonary fluid status according to Enghardt et al. 2015).
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03768752
|Contact: Ursula Kahl, MD||+49 (0) firstname.lastname@example.org|
|Contact: Katharina Röher, MDemail@example.com|
|Hamburg, Germany, 20246|
|Contact: Silke Schrum, Dr. +49 (0) 40 7410 - 54290 firstname.lastname@example.org|
|Principal Investigator:||Ursula Kahl, MD||Klinik und Poliklinik für Anästhesie Universitätsklinikum Hamburg-Eppendorf|