The Impact of Anxiety or Depression on the Sedative Concentration of Propofol
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|ClinicalTrials.gov Identifier: NCT03741361|
Recruitment Status : Completed
First Posted : November 14, 2018
Last Update Posted : July 9, 2019
|Condition or disease||Intervention/treatment|
|Anxiety Depression Propofol Anesthetics, Intravenous||Other: anxiety and depression|
|Study Type :||Observational|
|Actual Enrollment :||120 participants|
|Official Title:||The Impact of Anxiety or Depression on the Sedative Concentration of Propofol in Day-case Hysteroscopic Surgery: a Prospective Observational Study|
|Actual Study Start Date :||November 27, 2018|
|Actual Primary Completion Date :||February 1, 2019|
|Actual Study Completion Date :||February 15, 2019|
Anxiety and Depression
Female patients scheduled for hysteroscopic surgery under propofol-based intravenous anesthesia will be recruited in this prospective cohort study.
Other: anxiety and depression
Female patients who have a previous history of surgery or infertility, or a history of miscarriage or abortion are often susceptible to preoperative anxiety or depression. We will observe the effect of anxiety and depression on the dosage of propofol during induction.
- Effect-site concentration (Ce) of propofol [ Time Frame: Time of induction is less than 10 minutes. ]Effect-site concentration (Ce) of propofol on the TCI-system at the sedative level of OAA/S score of 3, OAA/S score of 1, and OAA/S core of 1 and NI<64 reached will be recorded.
- The induction dose of propofol [ Time Frame: Time of induction is less than 10 minutes. ]The dose of propofol required at the sedative level of OAA/S score of 3, OAA/S score of 1, and OAA/S core of 1 and NI<64 reached will be recorded.
Biospecimen Retention: Samples Without DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03741361
|The First Affiliated Hospital of Sun Yat-sen University|
|Guangzhou, Guangdong, China, 510000|
|Principal Investigator:||Xuyu Zhang, M.D. and Ph.D||Department of Anesthesiology,The first affiliated hospital of Sun Yat-sen University|