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Activation Patterns of Respiratory Muscles to Loaded Inspiratory Muscle Tests in Healthy Adults Under Different Posture

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ClinicalTrials.gov Identifier: NCT03729986
Recruitment Status : Completed
First Posted : November 5, 2018
Last Update Posted : February 12, 2019
Sponsor:
Information provided by (Responsible Party):
National Taiwan University Hospital

Brief Summary:
Whether minimizing sternocleidomastoid (SCM) activation in supine position would increase diaphragm activation during loaded inspiratory muscle tests remains to be determined. Therefore, the purpose is to exam diaphragm and SCM activation during loaded inspiratory muscle tests in sitting and supine position in healthy adults.

Condition or disease Intervention/treatment
Accessory Muscle Other: Loaded inspiratory muscle test

Detailed Description:
Inspiratory muscle training usually performed in the upright sitting position. In healthy individuals, sternocleidomastoid (SCM) is rarely recruited during tidal breathing, but previous studies have demonstrated SCM activation during loaded inspiratory muscle tests in upright sitting position. Whether minimizing SCM activation in supine position would increase diaphragm activation during loaded inspiratory muscle tests remains to be determined. Therefore, the purpose is to exam diaphragm and SCM activation during loaded inspiratory muscle tests in sitting and supine position in healthy adults.

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Study Type : Observational
Actual Enrollment : 14 participants
Observational Model: Other
Time Perspective: Cross-Sectional
Official Title: Activation Patterns of Respiratory Muscles to Loaded Inspiratory Muscle Tests in Healthy Adults Under Different Posture
Actual Study Start Date : November 1, 2018
Actual Primary Completion Date : December 28, 2018
Actual Study Completion Date : December 28, 2018

Resource links provided by the National Library of Medicine


Group/Cohort Intervention/treatment
Healthy adults
Healthy subjects without exercise habit that can cooperate with the measurements of this study, loaded inspiratory muscle test.
Other: Loaded inspiratory muscle test
Loaded inspiratory muscle tests will be set at 30% of maximal inspiratory pressure in sitting and supine positions. The orders of the two loaded test conditions will be conducted in random order with at least 20 minute separation. This is an observational study. Subjects will perform only 15 breaths with each loaded test condition to exam the performance of their inspiratory muscles. Loaded inspiratory muscle test is not for training.




Primary Outcome Measures :
  1. Diaphragm and Sternocleidomastoid muscle activation [ Time Frame: Through the completion of the loaded inspiratory muscle test condition; it would take about 3 minutes ]
    Root mean square values during different conditions

  2. The mean median frequency of diaphragm and sternocleidomastoid muscle [ Time Frame: In one minute after the completion of the loaded inspiratory muscle test condition ]
    The power spectrum is divided into two equal areas of the frequency value by median frequency to exam muscle fatigability



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Ages Eligible for Study:   20 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Healthy adults that are willing to cooperate the measurement of this study.
Criteria

Inclusion Criteria:

  • age > 20 years old
  • without exercise habit (any exercise that less than 3 days/week)
  • can cooperate with the measurements of this study

Exclusion Criteria:

  • any clinical diagnosis that will influence the measurement, including any history of neuromyopathy
  • angina, acute myocardial infarction in the previous one month
  • pregnancy
  • participated in inspiratory muscle training program in the previous three months
  • any psychiatric or cognitive disorders, for example: Mini-Mental State Examination (MMSE) < 24, that will disturb the communication and cooperation of the study

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03729986


Locations
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Taiwan
School and Graduate Institute of Physical Therapy of National Taiwan University
Taipei, Zhongzheng Dist, Taiwan, 100
Sponsors and Collaborators
National Taiwan University Hospital
Investigators
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Study Chair: Li-Ying Wang, Phd National Taiwan University
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Responsible Party: National Taiwan University Hospital
ClinicalTrials.gov Identifier: NCT03729986    
Other Study ID Numbers: 201807021RINA
First Posted: November 5, 2018    Key Record Dates
Last Update Posted: February 12, 2019
Last Verified: November 2018

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Additional relevant MeSH terms:
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Respiratory Aspiration
Respiration Disorders
Respiratory Tract Diseases
Pathologic Processes