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Causality of Poisoning of the Elderly: Prospective Study Based on Data From the Poison Control Centre of Bordeaux (GERIATOX)

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ClinicalTrials.gov Identifier: NCT03726632
Recruitment Status : Completed
First Posted : October 31, 2018
Last Update Posted : October 31, 2018
Sponsor:
Information provided by (Responsible Party):
University Hospital, Bordeaux

Study Description
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Brief Summary:

Elderly is often associated with social, physiological and psychic changes. However, no study has examined accidental poisoning-induced changes.

The objective of the study is to identify and analyze the various causes of potentially toxic accidental exposure of the elderly to determine preventable causes and propose prevention strategies.


Condition or disease
Intoxication

Detailed Description:

Elderly is often associated with social, physiological and psychic changes. Many studies tried to demonstrate their influence in the genesis of pathological events such as falls or suicide of the elderly but none on the genesis of accidental poisoning.

However, poisoning in this age group is frequent and sometimes severe. In order to improve care of the elderly, it seems necessary to focus on potential toxic accidental exposure.

For this, Poison Control Centre of the University Hospital of Bordeaux has identified the causes over a period of 5 months (from 01 March to 31 July 2017) from calls to the centre.


Study Design
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Study Type : Observational
Actual Enrollment : 122 participants
Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Causality of Poisoning of the Elderly: Prospective Study Based on Data From the Poison Control Centre of Bordeaux Over 5 Months
Actual Study Start Date : April 3, 2017
Actual Primary Completion Date : August 2, 2017
Actual Study Completion Date : August 2, 2017

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Poisoning

Groups and Cohorts
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Outcome Measures
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Primary Outcome Measures :
  1. Nature of the agent [ Time Frame: Baseline ]
    The nature of the agent has to be chosen among (1 choice only): drug, chemical, household product, DIY product, phytosanitary product, gas, plant, foreign body, food


Secondary Outcome Measures :
  1. Circumstance of the event [ Time Frame: Baseline ]
    The circumstance of the event has to be chosen among (1 choice only): accidental / voluntary

  2. Exposition route of exposure [ Time Frame: Baseline ]
    The exposition route of exposure has to be chosen among (1 choice only): ingestion, eyepiece, dermal, inhalation or multiple routes

  3. symptoms [ Time Frame: Baseline ]
    Number / Nature

  4. Poisoning Severity [ Time Frame: Baseline ]
    The poisoning severity is evaluated using the Poisoning Severity Scale (PSS score). Severity grades: None (No symptoms or signs related to poisoning); MINOR (Mild, transient and spontaneously resolving symptoms); MODERATE (Pronounced or prolonged symptoms); SEVERE (Severe or life-threatening symptoms); DEATH

  5. Death [ Time Frame: Baseline ]
    death before the call

  6. Frailty status [ Time Frame: Baseline ]
    The frailty status is calculated from the following factors: sensory disturbance, cognitive and/or neurological disorder, psychiatric disorder, autonomy / dependence, concomittant treatments

  7. packaging of the agent [ Time Frame: Baseline ]
    The packaging of the agent has to be chosen among (1 choice only): solid, liquid, gaseous, powder and if drug: tablet, drops, syrup, patch, injectable

  8. Concomittant treatment [ Time Frame: Baseline ]
    Number of prescription drugs


Eligibility Criteria
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Ages Eligible for Study:   65 Years and older   (Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
All subjects aged 65 and over, victims of accidental or voluntary (excepted suicide) exposure of an agent (drug, household product, plant ...) and for who a call the Bordeaux Poison Control Centre has been called.
Criteria

Inclusion Criteria:

  • All subjects aged 65 and over,
  • Victims of accidental exposure regardless of the agent (drug, household product, plant ...)
  • Victims of voluntary exposure (out of suicidal behavior)
  • And for which a call (notice, report) to the Poison Control Centre of Bordeaux has been recorded.
  • Calling dates between March 1st and July 31st, even if the exhibition is prior to March 1st, 2017).

Exclusion Criteria:

  • Suicide
  • Calls for inquiries
Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03726632


Locations
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France
Centre Anti Poision du CHU de Bordeaux
Bordeaux, France
Sponsors and Collaborators
University Hospital, Bordeaux
More Information
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Responsible Party: University Hospital, Bordeaux
ClinicalTrials.gov Identifier: NCT03726632     History of Changes
Other Study ID Numbers: CHUBX 2017/02
First Posted: October 31, 2018    Key Record Dates
Last Update Posted: October 31, 2018
Last Verified: October 2018
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by University Hospital, Bordeaux:
Elderly
Intoxication
Poison Control centre
 Poisoning
Accidental exposure
Prevention
Additional relevant MeSH terms:
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Poisoning
Chemically-Induced Disorders