Working…
COVID-19 is an emerging, rapidly evolving situation.
Get the latest public health information from CDC: https://www.coronavirus.gov.

Get the latest research information from NIH: https://www.nih.gov/coronavirus.
ClinicalTrials.gov
ClinicalTrials.gov Menu

Locally Injected Vit D as a Non-surgical Modality for Periodontal Regeneration of Infrabony Defects

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT03716765
Recruitment Status : Completed
First Posted : October 23, 2018
Last Update Posted : October 23, 2018
Sponsor:
Information provided by (Responsible Party):
nermin mohammed ahmed yussif, Cairo University

Brief Summary:
vitamin D has great role in bone regenration and soft tissue health. in the past periodontal regeneration was performed using bone graft and barrier membrane

Condition or disease Intervention/treatment Phase
Periodontal Bone Loss Periodontal Pocket Dietary Supplement: locally injected vitamin D Not Applicable

Detailed Description:
there was no previous studies used the locally injected vitamin d in periodontal regeneration. therefore, we intended to study the effect of locally injected vitamin D in peridoontal regerneration in comparison with the conventional surgical technique

Layout table for study information
Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 20 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Care Provider, Investigator)
Primary Purpose: Treatment
Official Title: Locally Injected Vitamin D as a Non-surgical Modality for Periodontal Regeneration of Infrabony Defects: Prospective Study
Actual Study Start Date : January 2016
Actual Primary Completion Date : January 2018
Actual Study Completion Date : June 2018

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Vitamin D
Drug Information available for: Vitamin D

Arm Intervention/treatment
Experimental: non-surgical periodontal regeneration
non-surgical periodontal regeneration using locally injected vitamin d to treat the infrabony defect
Dietary Supplement: locally injected vitamin D
locally injected vitamin d as non surgical method for periodontal regeneration of vertical bony defects
Other Name: non-surgical periodontal rgeneration

Active Comparator: surgical peridoontal regeneration
surgical periodontal regeneration using bone graft and collagen barrier
Dietary Supplement: locally injected vitamin D
locally injected vitamin d as non surgical method for periodontal regeneration of vertical bony defects
Other Name: non-surgical periodontal rgeneration




Primary Outcome Measures :
  1. radiographic interproximal bone level [ Time Frame: 6 months ]
    radiographic interproximal bone level



Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Layout table for eligibility information
Ages Eligible for Study:   20 Years to 45 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • patients with infrabony vertical defects
  • systemically free patients
  • periodontally affected patients

Exclusion Criteria:

  • patients with systemic diseases
  • smokers
  • pregnency

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03716765


Sponsors and Collaborators
Cairo University
Investigators
Layout table for investigator information
Study Director: nermin yussif october university of modern sciences and arts

Layout table for additonal information
Responsible Party: nermin mohammed ahmed yussif, assistant lecturer, Cairo University
ClinicalTrials.gov Identifier: NCT03716765    
Other Study ID Numbers: 1236
First Posted: October 23, 2018    Key Record Dates
Last Update Posted: October 23, 2018
Last Verified: October 2018
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

Layout table for additional information
Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Product Manufactured in and Exported from the U.S.: No
Additional relevant MeSH terms:
Layout table for MeSH terms
Alveolar Bone Loss
Periodontal Pocket
Periodontitis
Periodontal Diseases
Mouth Diseases
Stomatognathic Diseases
Bone Resorption
Bone Diseases
Musculoskeletal Diseases
Periodontal Atrophy
Vitamin D
Ergocalciferols
Vitamins
Micronutrients
Nutrients
Growth Substances
Physiological Effects of Drugs
Bone Density Conservation Agents
Calcium-Regulating Hormones and Agents