Collateral Circulation to LAD and Wellens Sign
|ClinicalTrials.gov Identifier: NCT03707626|
Recruitment Status : Unknown
Verified October 2018 by George Juang, Coney Island Hospital, Brooklyn, NY.
Recruitment status was: Recruiting
First Posted : October 16, 2018
Last Update Posted : October 16, 2018
Overall Aim Coronary artery disease significantly contributes to morbidity and mortality in the United States. Atherosclerotic disease can lead to stenosis of the coronary arteries and subsequent cardiac hypoperfusion. Patients with a critical stenosis of the LAD, potentially leading to acute anterior wall myocardial infarction, may be asymptomatic at presentation with subtle EKG changes as its only manifestation. It is imperative for physicians to recognize patients with new T wave inversions in leads V2-V3 as the standard course of management may lead to poor prognosis.
The purpose of this study is to determine if collateral circulation to the left anterior descending (LAD) artery will mask the presence of a Wellens sign and therefore diminish its diagnostic utility. The conclusion of this study would raise awareness for physicians in light of an absent Wellens sign.
Hypothesis The presence of coronary collateral circulation to the LAD masks the presence of a Wellens sign (both Type 1 and Type 2) in precordial leads V2-V4.
|Condition or disease||Intervention/treatment|
|Coronary Artery Disease Acute Myocardial Infarction Acute Myocardial Infarction of Anterior Wall Collateral Circulation, Any Site||Other: Wellens Sign|
|Study Type :||Observational|
|Estimated Enrollment :||1500 participants|
|Official Title:||Does Coronary Collateral Circulation Mask the Presence of a Wellens Sign in Patients With Critical Stenosis of the Left Anterior Descending Artery?|
|Actual Study Start Date :||September 26, 2018|
|Estimated Primary Completion Date :||June 23, 2019|
|Estimated Study Completion Date :||June 23, 2019|
|LAD with collaterals with and without wellens sign||
Other: Wellens Sign
presence or absence in presence of coronary collaterals to LAD
- Wellens Sign [ Time Frame: 2003-2016 ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03707626
|Contact: Ida H Suen, MDemail@example.com|
|Contact: George Juang, MD|
|United States, New York|
|Coney Island Hospital||Recruiting|
|Brooklyn, New York, United States, 11235|
|Contact: Ida H Suen, MD 941-228-9020 firstname.lastname@example.org|
|Sub-Investigator: Ida H Suen, MD|
|Principal Investigator: George Juang, MD|
|Sub-Investigator: Adil Ali, MD|
|Principal Investigator:||George Juang, MD||Coney Island Hospital|