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Trial record 62 of 82733 for:    measured

Functional Residual Capacity Measured by Capnography in Ventilated Patients

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT03693352
Recruitment Status : Recruiting
First Posted : October 3, 2018
Last Update Posted : November 26, 2019
Sponsor:
Information provided by (Responsible Party):
Hospital Privado de Comunidad de Mar del Plata

Brief Summary:
Changes in body position during anesthesia can alter functional residual capacity and gas exchange. The monitoring of such changes in functional residual capacity is difficult at the bedside. The present study was designed to determine if volumetric capnography can detect changes in the functional residual capacity during surgery.

Condition or disease
Respiratory Physiological Phenomena

Detailed Description:
This is a prospective and observational study designed to test the reliability of the capnodynamic equation to determine changes in functional residual capacity measured during anesthesia. The investigators will studied 40 mechanically ventilated patients undergoing general anesthesia. Functional residual capacity will be continuously measured in a non invasive way using expired carbon dioxide. Changes in functional residual capacity with standard modification in body positioning (Trendelenburg or anti-Trendelenburg position) and ventilatory settings wiil be tested.

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Study Type : Observational
Estimated Enrollment : 40 participants
Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Effect of Positive End-expiratory Pressure on Functional Residual Capacity Measured by Volumetric Capnography in Mechanically Ventilated Patients
Actual Study Start Date : October 1, 2018
Estimated Primary Completion Date : December 31, 2019
Estimated Study Completion Date : January 30, 2020

Group/Cohort
Patients undergoing surgeries
Patients ASA 1-3, undergoing different types of general anesthesia that need postural changes like Trendelenburg and anti-Trendelenburg positioning.



Primary Outcome Measures :
  1. Functional Residual Capacity Measured by Capnography in Ventilated Patients [ Time Frame: 6 hours ]
    Measurement of functional residual capacity with capnography with body positioning changes.



Information from the National Library of Medicine

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Ages Eligible for Study:   30 Years to 80 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients undergoing general anesthesia for laparoscopic surgery
Criteria

Inclusion Criteria:

  • Written Inform Consent
  • Programmed surgery
  • Laparoscopic surgery
  • Supine position

Exclusion Criteria:

  • Emergency surgery
  • Chronic respiratory disease
  • Active smoking

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03693352


Contacts
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Contact: Cecilia Acosta, MD 542234990074 ceciliamacosta@hotmail.com
Contact: Esteban Gándara, MD 542234990099 gandara.esteban@gmail.com

Locations
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Argentina
Hospital Privado de Comunidad Recruiting
Mar del Plata, Buenos Aires, Argentina, 7600
Contact: Esteban Gandara, MD    542234990099    gandara.esteban@gmail.com   
Sponsors and Collaborators
Hospital Privado de Comunidad de Mar del Plata
Investigators
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Principal Investigator: Gerardo Tusman, MD Hospital Privado de Comunidad de Mar del Plata

Publications:
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Responsible Party: Hospital Privado de Comunidad de Mar del Plata
ClinicalTrials.gov Identifier: NCT03693352    
Other Study ID Numbers: 2919/1728/18
First Posted: October 3, 2018    Key Record Dates
Last Update Posted: November 26, 2019
Last Verified: September 2019
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No