the Related Factors of Bariatric Surgery on Bone Mineral Density
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|ClinicalTrials.gov Identifier: NCT03689816|
Recruitment Status : Unknown
Verified September 2018 by Jingge Yang, First Affiliated Hospital of Jinan University.
Recruitment status was: Active, not recruiting
First Posted : September 28, 2018
Last Update Posted : September 28, 2018
Obesity and related metabolic diseases have become a chronic disease that is a threat to human health. Bariatric surgery can effectively and long-term reduce excess body weight and relieve related metabolic diseases, including type 2 diabetes. Laparoscopic gastric bypass surgery and laparoscopic sleeve gastrectomy are commonly used in bariatric surgery. Laparoscopic sleeve gastrectomy due to simple operation, good weight loss, and metabolic disease control effect, which is more widely used. However, there are several studies that show an increased chance of gastroesophageal reflux disease after laparoscopic sleeve gastrectomy. Long-term gastroesophageal reflux may lead to Barrett's esophagus or esophageal cancer. Nowadays, the cause of gastroesophageal reflux disease after sleeve gastrectomy is not clear and precautionary measures are not precise.
In this study, prospective randomized controlled trials were conducted to explore the possible causes of bone mineral after bariatric surgery and to explore ways to prevent bone mineral after bariatric surgery.
|Condition or disease||Intervention/treatment||Phase|
|Bone Mineral Bariatric Surgery||Procedure: sleeve gastrectomy Procedure: gastric bypass||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||1000 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||The Impact of Bariatric Surgery on Estimated Bone Mineral Density in Chinese Obesity Patients: a Retrospective Cohort Study|
|Actual Study Start Date :||April 1, 2018|
|Estimated Primary Completion Date :||December 2018|
|Estimated Study Completion Date :||December 2019|
Experimental: bone density
Procedure: sleeve gastrectomy
Procedure: gastric bypass
- Preoperative of bone density [ Time Frame: Preoperative ]bone density in g/cm3
- Postoperative of bone density at 3 months [ Time Frame: 3 months ]bone density in g/cm3
- Postoperative of bone density at 6 months [ Time Frame: 6 months ]bone density in g/cm3
- Postoperative of bone density at 1 year [ Time Frame: 1 year ]bone density in g/cm3
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03689816
|The frist affiliated hospital of Jinan University|
|Guangzhou, Guangdong, China, 510630|