Opportunities and Limits to Deprescribing in Nursing Homes:Quality Circle Deprescribing Module (OLD-NH-QC-DeMo)
|ClinicalTrials.gov Identifier: NCT03688542|
Recruitment Status : Active, not recruiting
First Posted : September 28, 2018
Last Update Posted : April 3, 2020
Older people residing in nursing homes (NH) are frequently polymedicated and often prescribed potentially inappropriate medications. Deprescribing has been proposed as a way to reduce the number of drugs they receive and their exposure to harmful treatments.
The objectives of this study are 1) To evaluate the effect of a deprescribing-specific interdisciplinary quality circle module on the use of potentially inappropriate medication in nursing-home residents. 2) To determine the effective strategies to reach and implement deprescribing consensus resulting of said quality circle module.
|Condition or disease||Intervention/treatment||Phase|
|Polypharmacy Inappropriate Prescribing||Other: Quality Circle Deprescribing Module||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||62 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Single (Outcomes Assessor)|
|Official Title:||Opportunities and Limits to Deprescribing in Nursing Homes:Quality Circle Deprescribing Module|
|Actual Study Start Date :||September 25, 2017|
|Estimated Primary Completion Date :||June 2020|
|Estimated Study Completion Date :||June 2020|
Nursing Homes allocated to the Intervention arm will enact the Quality Circle Deprescribing Module and create a local deprescribing consensus and implementation strategy.
Other: Quality Circle Deprescribing Module
The Quality Circle Deprescribing Module consist of a discussion bringing together nurses, physicians and responsible pharmacist to create a local deprescribing consensus for frequently used drug classes, as well as implementation strategies for the consensus..
No Intervention: Control
Nursing Homes allocated to the Control arm will not enact the intervention.
- Change in the proportion of PIMs use [ Time Frame: 12 months ]The primary outcome is the change at 12 months, relative to baseline, in the proportion of Potentially Inappropriate medication (PIMs) used in the NHs relative to their total drug consumption
- Change in the number of potentially inappropriate Defined Daily Doses (DDDs) per average resident and per day [ Time Frame: 12 months ]Sum of Defined Daily Doses identified as potentially inappropriate, divided by the total number of days spent in the NH
- Difference in proportion of probably inappropriate galenic units and of possibly inappropriate galenic units [ Time Frame: 12 months ]
- Difference in proportion of probably inappropriate Defined Daily Doses (DDDs) and of possibly inappropriate DDDs: [ Time Frame: 12 months ]
- Number of hospital days [ Time Frame: 12 months ]The number of days spent in the hospital by residents in the nursing home
- Mortality rate [ Time Frame: 12 months ]The proportion of residents of the nursing home having died
- Number of falls per mean resident and per month [ Time Frame: 12 months ]
- Number of restraints measures per mean resident and per month [ Time Frame: 12 months ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03688542
|Centre de Pharamacie Communautaire|
|Lausanne, Vaud, Switzerland, 1011|
|Study Director:||Olivier Bugnon, Prof||University of Geneva|