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The Correlation Between Sevoflurane and qNOX

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ClinicalTrials.gov Identifier: NCT03665792
Recruitment Status : Recruiting
First Posted : September 11, 2018
Last Update Posted : February 19, 2019
Sponsor:
Information provided by (Responsible Party):
China International Neuroscience Institution

Brief Summary:
This study purpose to observation the sevoflurane analgesia effect, and using nociception real-time monitoring NOX to test the correlation between the sevoflurane and NOX index.

Condition or disease Intervention/treatment
Analgesic Adverse Reaction Nociceptive Pain Inhalation; Vapor Device: nociception index qNOX

Detailed Description:

This study purpose to observation the sevoflurane analgesia effect, and using nociception real-time monitoring NOX to test the analgesia effect of the sevoflurane.

And test the correlation between the sevoflurane and NOX index.


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Study Type : Observational
Estimated Enrollment : 89 participants
Observational Model: Other
Time Perspective: Cross-Sectional
Official Title: The Prospective Observational Research of the Analgesic Effect of Sevoflurane and the Correlation Between Sevoflurane and qNOX
Actual Study Start Date : February 11, 2019
Estimated Primary Completion Date : August 28, 2019
Estimated Study Completion Date : December 30, 2019

Resource links provided by the National Library of Medicine

Drug Information available for: Sevoflurane


Intervention Details:
  • Device: nociception index qNOX
    non-invasive, real time, monitoring for nociception stimulation
    Other Name: CON , BIS


Primary Outcome Measures :
  1. The sevoflurane application correlated with the qNOX index [ Time Frame: through study completion, an average of 1 year ]
    The sevoflurane application correlated with the qNOX index, meanwhile reflect the analgesia effect of sevoflurane application



Information from the National Library of Medicine

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Ages Eligible for Study:   25 Years to 85 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
only elective thoracoscope surgery patients were enrolled
Criteria

Inclusion Criteria:

  1. Elective thoracoscope surgery patients
  2. Age ranging from 25 to 85 years
  3. American Society of Anesthesiologists (ASA) Physical Status score of 2 to 4
  4. a body mass index (BMI) ranging from 18.5 to 40 kg/m2.

Exclusion Criteria:

  1. Clinical diagnosis of Alzheimer's Disease
  2. implanted pacemaker
  3. Clinical diagnosis of psychiatric diseases
  4. Clinical diagnosis of epilepsy
  5. Clinical diagnosis of autonomic nervous system disorders which might affect the EEG

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03665792


Contacts
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Contact: Tianlong Wang, PHD 15910851623 ext 15910851623 w_tl5595@yahoo.com
Contact: Zhaolong Tian, MS 15010283592 ext 15910851623 1055885750@qq.com

Locations
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China, Beijing
Bei Liu Recruiting
Beijing, Beijing, China, 100053
Contact: Zhaolong Tian    15010283592 ext 15010283592    1055885750@qq.com   
Contact: Tianlong Wang    8901-83199933    w_tl5595@yahoo.com   
Principal Investigator: Xiaohua Wang         
Sponsors and Collaborators
China International Neuroscience Institution
Investigators
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Principal Investigator: Xiaohua Wang, MD,PHD Xuanwu Hospital, Beijing

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Responsible Party: China International Neuroscience Institution
ClinicalTrials.gov Identifier: NCT03665792     History of Changes
Other Study ID Numbers: CINI-ZYLX-201806-11
First Posted: September 11, 2018    Key Record Dates
Last Update Posted: February 19, 2019
Last Verified: February 2019
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No

Additional relevant MeSH terms:
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Nociceptive Pain
Pain
Neurologic Manifestations
Signs and Symptoms
Sevoflurane
Platelet Aggregation Inhibitors
Anesthetics, Inhalation
Anesthetics, General
Anesthetics
Central Nervous System Depressants
Physiological Effects of Drugs