Comparison of Neuromuscular Block (NMB) Depth Measured by Two Monitors.
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|ClinicalTrials.gov Identifier: NCT03660891|
Recruitment Status : Recruiting
First Posted : September 7, 2018
Last Update Posted : September 7, 2018
|Condition or disease||Intervention/treatment|
|Neuromuscular Blockade||Diagnostic Test: measuring neuromuscular block|
NMT (neuromuscular transmission) depth can be measured at the same arm with two different methods during clinical practice.
the first (TOF Watch) measures the musculus adductor pollicis acceleration while the second method (TOF Cuff Monitor) uses a blood pressure cuff to measure the pressure changes induced by the upper arm muscles.
During general anesthesia when NMB (neuromuscular block) is required both methods are used. Every 5 minutes, if clinical required, the NMB is monitored by TOF-PTC. If the measurement of TOF is zero the monitor continues by measuring PTC ( the system will measure TOF followed by PTC if TOF is zero) TOF-PTC is recorded and later compared for identity or systematic difference in one or the other direction.
The measured answer can be TOF 4 (4 answers) with a ratio between answer 1 and 4 expressed and a percentage, TOF 3 (3 answers), TOF 2, TOF 1, TOF 0 + PTC 20, TOF 0 + PTC 19, up to TOF 0 + PTC 0
|Study Type :||Observational|
|Estimated Enrollment :||20 participants|
|Official Title:||Comparison of Neuromuscular Block Depth Measured by a TOF (Train of Four) Watch and a TOF Cuff Monitor on the Same Arm of the Same Patient.|
|Actual Study Start Date :||March 1, 2018|
|Estimated Primary Completion Date :||June 30, 2019|
|Estimated Study Completion Date :||December 31, 2019|
- Diagnostic Test: measuring neuromuscular block
During anesthesia patients are monitored with two instead of one NMT monitor. the difference in measured TOF-PTC is compared
- TOF-PTC value [ Time Frame: From induction of anesthesia (intubation with ETT) till end of anesthesia (extubation of ETT) most frequent between 1 and 2 hours, max 6 hours in duration ]Difference in TOF-PTC measured by two different devices during anesthesia.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03660891
|Contact: Jan Paul Mulier, MD PhDemail@example.com|
|Contact: Kris Leleu, MD||003250452498|
|Brugge, Belgium, 8000|
|Contact: j p mulier, MD PhD 00 32 50 45 21 93 firstname.lastname@example.org|
|Principal Investigator: jan P mulier, PhD|
|Study Chair:||Marco Lanckneus||AZ Sint Jan Brugge-Oostende|