Effect of Location of Tetanic Stimuli on Photoplethysmogram
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.
Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT03648853
Recruitment Status :
First Posted : August 27, 2018
Last Update Posted : January 10, 2019
University of California, San Francisco
Information provided by (Responsible Party):
Pekka Talke, University of California, San Francisco
The effect of the location of tetanic stimulus on photoplethysmography signals will be studies in patients under general anesthesia.
Condition or disease
Device: Tetanic Stimulus
A 5 second 100 Hz 70 mA tetanic stimulus will be applied to three different locations in a random order in patients who are under general anesthesia. Tetanic stimuli are used routinely during general anesthesia to assess effectiveness of neuromuscular blockade. These tetanic stimuli are noxious stimuli that elicit a stress response which can be quantified using photoplethysmography. This study investigates if the magnitude of the tetanus induced stress response is dependent on the location of the tetanic stimulus as measured by photoplythysmography.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Layout table for eligibility information
Ages Eligible for Study:
18 Years and older (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Surgical patients general anesthesia able to consent in english
regional anesthesia unable to consent in english under 18 yrs of age