Single Dose Tranexamic Acid in Reducing Blood Loss During Cytoreductive Surgery and HIPEC
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|ClinicalTrials.gov Identifier: NCT03646474|
Recruitment Status : Recruiting
First Posted : August 24, 2018
Last Update Posted : December 27, 2018
|Condition or disease||Intervention/treatment||Phase|
|Cytoreductive Surgery||Drug: tranexamic Acid infusion Drug: saline infusion||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||46 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Double (Participant, Care Provider)|
|Official Title:||Evaluation of the Efficacy & Safety of a Single Dose Tranexamic Acid in Reducing Blood Loss During Cytoreductive Surgery and HIPEC|
|Actual Study Start Date :||August 30, 2018|
|Estimated Primary Completion Date :||January 1, 2019|
|Estimated Study Completion Date :||January 15, 2019|
|Active Comparator: tranexamic acid group||
Drug: tranexamic Acid infusion
The tranexamic Acid group will receive an intravenous bolus of (10 mg/kg) in 100 ml of normal saline over 20 minutes after induction of anesthesia and before surgical incision.
|Placebo Comparator: placebo group||
Drug: saline infusion
In the placebogroup, patients will receive a placebo of 100 mL 0.9% normal saline.
- change in blood loss [ Time Frame: 1st 24 hours. ]Blood loss will be calculated (volume estimated as the blood remaining in sponges and drapes and the volume in suction bottles during surgery).
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03646474
|Contact: Ahmed Othmanemail@example.com|
|National Cancer Institute, Cairo University||Recruiting|
|Contact: Ekramy Mansour, MD 00201224642810 firstname.lastname@example.org|