Does Propranolol, a Beta Blocker, Attenuate Stress-Induced Drinking?
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT03588754|
Recruitment Status : Recruiting
First Posted : July 17, 2018
Last Update Posted : July 8, 2019
|Condition or disease||Intervention/treatment||Phase|
|Alcohol Drinking||Drug: Propranolol Drug: Placebo||Phase 2|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||20 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)|
|Official Title:||Does Propranolol, a Beta Blocker, Attenuate Stress-Induced Drinking?|
|Actual Study Start Date :||September 15, 2018|
|Estimated Primary Completion Date :||July 31, 2019|
|Estimated Study Completion Date :||July 31, 2019|
Propranolol extended release (160mg/day). Administered orally once daily at 10:00PM. Titration schedule Days 1-3 60mg, Days 4-7 80mg, Days 8-11 120mg, and Days 12-14 160mg until steady state.
Propranolol Extended Release (160mg/day).
Placebo Comparator: Placebo
Administered orally once daily at 10:00PM
Placebo pill administered orally.
- Alcohol consumption [ Time Frame: 120 minutes ]Mean mls of alcohol consumed (maximum of 120 mg/dL) for propranolol and placebo groups during 120 minute alcohol self administration sessions taking place as close to Day 15 and Day 19 as possible of medication dosing.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03588754
|Contact: Sabrina Coppolaemail@example.com|
|Contact: Paula Cunninghamfirstname.lastname@example.org|
|United States, Connecticut|
|Yale University School of Medicine||Recruiting|
|New Haven, Connecticut, United States, 06519|
|Contact: Sabrina Coppola 203-737-2827 email@example.com|
|Contact: Paula Cunningham 203-785-3547 firstname.lastname@example.org|
|Principal Investigator:||Sherry McKee, PhD||Professor|