COVID-19 is an emerging, rapidly evolving situation.
Get the latest public health information from CDC:

Get the latest research information from NIH: Menu

Acute Kidney Injury in Neonates at NICU in Assiut University Children Hospital Descriptive Study

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT03528837
Recruitment Status : Unknown
Verified May 2018 by Mohammed Ali Abdelrhman, Assiut University.
Recruitment status was:  Not yet recruiting
First Posted : May 18, 2018
Last Update Posted : May 18, 2018
Information provided by (Responsible Party):
Mohammed Ali Abdelrhman, Assiut University

Brief Summary:
Acute kidney injury (AKI) is a complex disorder with clinical manifestations ranging from mild dysfunction to complete anuric kidney failure. Its leads to sudden and rapid decline in renal excretory function within hours to days,accompanied by accumulation of nitrogenous waste products such creatinine,urea and other clinically un measured products

Condition or disease
Neonatal Acute Kidney Injury

Detailed Description:
Acute kidney injury (AKI) is an under-recognized morbidity of neonates; the incidence remains unclear due to the absence of a unified definition of AKI in this population and because previous studies have varied greatly in screening for AKI with serum creatinine and urine output assessments. Premature infants may be born with less than half of the nephrons compared with term neonates, predisposing them to chronic kidney disease (CKD) early on in life and as they age. AKI can also lead to CKD, and premature infants with AKI may be at very high risk for long-term kidney problems. AKI in neonates is often multifactorial and may result from prenatal, perinatal, or postnatal insults as well as any combination thereof.

Layout table for study information
Study Type : Observational
Estimated Enrollment : 30 participants
Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Acute Kidney Injury in Neonates at NICU in Assiut University Children Hospital Descriptive Study
Estimated Study Start Date : June 30, 2018
Estimated Primary Completion Date : July 1, 2019
Estimated Study Completion Date : August 1, 2019

Resource links provided by the National Library of Medicine

Diagnosed as acute kidney injury
Sure diagnosed as acute kidney injury

Primary Outcome Measures :
  1. Diagnosed as acute kidney injury [ Time Frame: 10-21 days ]
    Diagnosis of acute kidney injury

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Layout table for eligibility information
Ages Eligible for Study:   up to 28 Days   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Study of cases of acute kidney injury in neonates and its causes and it's outcome

Inclusion Criteria:

  • All cases of acute kidney injury in neonates who will be admitted to NICU Assiut University Children Hospital during the duration of the study.

Exclusion Criteria:

  • Cases with chronic renal affection Any case with congenital anomalies

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT03528837

Layout table for location contacts
Contact: Mustafa Sh Khalf, Professor +20112110096
Contact: Ahlam B Ali, Lectuer +201006807866

Layout table for location information
Assiut university children hospital
Assiut, Egypt
Contact: Mostafa Sh Khalf, Bachlear    +201112110096   
Sponsors and Collaborators
Assiut University
Layout table for additonal information
Responsible Party: Mohammed Ali Abdelrhman, Resident of neonatology, Assiut University Identifier: NCT03528837    
Other Study ID Numbers: AKI neonates
First Posted: May 18, 2018    Key Record Dates
Last Update Posted: May 18, 2018
Last Verified: May 2018

Layout table for additional information
Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Product Manufactured in and Exported from the U.S.: No
Additional relevant MeSH terms:
Layout table for MeSH terms
Acute Kidney Injury
Wounds and Injuries
Renal Insufficiency
Kidney Diseases
Urologic Diseases