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The Effect of NB-UVB on Interleukin-36 Levels in Psoriasis

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ClinicalTrials.gov Identifier: NCT03526705
Recruitment Status : Not yet recruiting
First Posted : May 16, 2018
Last Update Posted : May 16, 2018
Sponsor:
Information provided by (Responsible Party):
Dina Saadi, Cairo University

Brief Summary:

Psoriasis is an immune-mediated skin disease that affects 1-2 % of the population. Several cytokines have been found to be involved in the complex pathogenesis of this disease. Il- 36 is one of the cytokines sharing in psoriasis pathogenesis, as its levels are elevated in psoriatic plaques. NB-UVB is one of the important treatment modalities for psoriasis.

The aim of this study is to detect the effect of NB-UVB on the lesional levels of IL-36 in psoriasis.


Condition or disease Intervention/treatment
Psoriasis Device: NB-UVB

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Study Type : Observational
Estimated Enrollment : 40 participants
Observational Model: Case-Only
Time Perspective: Prospective
Official Title: The Effect of NB-UVB on Interleukin-36 Levels in Psoriasis Lesional Skin
Estimated Study Start Date : May 15, 2018
Estimated Primary Completion Date : November 15, 2018
Estimated Study Completion Date : December 15, 2018

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Psoriasis


Intervention Details:
  • Device: NB-UVB
    Phototherapy


Primary Outcome Measures :
  1. effect of NB-UVB on Il-36 levels in psoriasis [ Time Frame: 6 months ]
    primary



Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Egyptian males and females with psoriasis
Criteria

Inclusion Criteria:

  • Patients with psoriasis vulgaris of both sexes
  • Age between 18 and 60 years old.

Exclusion Criteria:

  • Pregnant females
  • Patients receiving systemic treatment or topical treatment for psoriasis within the past two months.
  • Patients having other dermatological diseases.

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Responsible Party: Dina Saadi, Lecturer, Cairo University
ClinicalTrials.gov Identifier: NCT03526705     History of Changes
Other Study ID Numbers: Kapu1
First Posted: May 16, 2018    Key Record Dates
Last Update Posted: May 16, 2018
Last Verified: May 2018
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: Undecided

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Studies a U.S. FDA-regulated Device Product: Yes
Device Product Not Approved or Cleared by U.S. FDA: No

Additional relevant MeSH terms:
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Psoriasis
Skin Diseases, Papulosquamous
Skin Diseases