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Trial record 32 of 761 for:    region | Chile

Response to Periodontal Therapy in a Chronic Kidney Disease Population

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ClinicalTrials.gov Identifier: NCT03525457
Recruitment Status : Recruiting
First Posted : May 15, 2018
Last Update Posted : August 31, 2018
Sponsor:
Information provided by (Responsible Party):
Maité Souyet, Pontificia Universidad Catolica de Chile

Brief Summary:
This study will evaluate periodontal and systemic parameters of a cohort of chronic kidney disease (stage 5) patients, before and three months after non-surgical periodontal treatment. It does not consider a control group.

Condition or disease Intervention/treatment Phase
Chronic Kidney Disease Stage 5 Periodontal Disease Procedure: Non Surgical Periodontal Therapy Not Applicable

Detailed Description:

Dental biofilm is a source of inflammation and infection of periodontal tissues. In the last 20 years the interaction between periodontal infections and systemic conditions has been largely studied, suggesting that the inflammation caused in the periodontal tissues could cause a response in other parts of the body.

Recent studies suggest that there could be an association between periodontal disease and chronic kidney disease.


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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 65 participants
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Response to Non Surgical Periodontal Therapy in a Chronic Kidney Disease Population Candidates to Kidney Transplant
Actual Study Start Date : August 6, 2018
Estimated Primary Completion Date : August 2019
Estimated Study Completion Date : December 2019

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Kidney Diseases

Arm Intervention/treatment
Experimental: Experimental
Non surgical periodontal therapy
Procedure: Non Surgical Periodontal Therapy
Non Surgical Periodontal Therapy in 2 to 3 sessions




Primary Outcome Measures :
  1. Change in Clinical Attachment Level (CAL) [ Time Frame: 3 months ]
    Change from baseline CAL (in mm) at three months


Secondary Outcome Measures :
  1. Change in Bleeding on probing (BOP) [ Time Frame: 3 months ]
    Change from baseline BOP (%) at three months



Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 65 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Chronic kidney disease patients in Stage 5 (candidates to renal transplant)

Exclusion Criteria:

  • Younger than 18 year old.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03525457


Contacts
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Contact: Maite C Souyet, MsC +56978786186 msouyet@gmail.com
Contact: Patricio F Smith, PhD psmithf@uc.cl

Locations
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Chile
Clínica Odontológica Docente UC Recruiting
Santiago, Región Metropolitana, Chile
Contact: Maite C Souyet, MsC    +56878786186    msouyet@gmail.com   
Sponsors and Collaborators
Pontificia Universidad Catolica de Chile
Investigators
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Principal Investigator: Maite C Souyet, MsC Pontificia Universidad Catolica de Chile

Publications:
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Responsible Party: Maité Souyet, DDS, MsC, Pontificia Universidad Catolica de Chile
ClinicalTrials.gov Identifier: NCT03525457     History of Changes
Other Study ID Numbers: 180104004
First Posted: May 15, 2018    Key Record Dates
Last Update Posted: August 31, 2018
Last Verified: August 2018
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: Undecided

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No

Keywords provided by Maité Souyet, Pontificia Universidad Catolica de Chile:
Glomerular filtration rate
Periodontitis
Chronic kidney disease

Additional relevant MeSH terms:
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Kidney Diseases
Renal Insufficiency, Chronic
Periodontal Diseases
Kidney Failure, Chronic
Urologic Diseases
Renal Insufficiency
Mouth Diseases
Stomatognathic Diseases