Dexmedetomidine on Segmental EEG Power Spectra
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|ClinicalTrials.gov Identifier: NCT03515876|
Recruitment Status : Recruiting
First Posted : May 4, 2018
Last Update Posted : April 9, 2019
|Condition or disease|
|Anesthesia EEG Power Spectra|
Three groups of patients undergoing hysteroscopic examination and surgery will be studied: 1) control group, patients will receive propofol intravenous infusion to provide anesthesia; 2) dexmedetomidine 0.5 microgram/kg group. This dexmedetomidine dose is infused within 10 min and then the use of propofol for anesthesia; and 3) dexmedetomidine 1 microgram/kg group. This dexmedetomidine dose is infused within 10 min and then the use of propofol for anesthesia.
Each group will have 20 patients.
General conditions including blood pressure, respiration, and heart rates will be recorded.
EEG power spectra activity will be recorded no-invasively by a Narcotrend EEG monitor.
|Study Type :||Observational|
|Estimated Enrollment :||60 participants|
|Official Title:||The Effects of Dexmedetomidine on Segmental EEG Power Spectra Activity Under Propofol-based Anesthesia|
|Actual Study Start Date :||April 19, 2018|
|Estimated Primary Completion Date :||June 2019|
|Estimated Study Completion Date :||July 2019|
Patients will receive intravenous propofol infusion.
Dexmedetomidine 0.5 microgram/kg group
Patients will receive dexmedetomidine 0.5 microgram/kg and then intravenous propofol infusion.
Dexmedetomidine 1 microgram/kg group
Patients will receive dexmedetomidine 1 microgram/kg and then intravenous propofol infusion.
- EEG power spectra [ Time Frame: From prior to anesthesia to 10 min after anesthesia. ]EEG power spectra monitored no-invasively by Narcotrend
- Blood pressure [ Time Frame: From prior to anesthesia to 10 min after anesthesia. ]Blood pressure monitored no-invasively
- Respiration [ Time Frame: From prior to anesthesia to 10 min after anesthesia. ]Monitored no-invasively
- Heart rates [ Time Frame: From prior to anesthesia to 10 min after anesthesia. ]Monitored no-invasively
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03515876
|Contact: Zhi Wang, MDfirstname.lastname@example.org|
|Sun Yat-Sen Memorial Hospital||Recruiting|
|Guangzhou, Guangdong, China, 510120|
|Contact: Wang Zhi, MD, Ph.D. 13622740039 email@example.com|
|Principal Investigator: Zhi Wang|