Pneumonia Due to Stenotrophomonas Maltophilia in ICUs (RETROSTENO)
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|ClinicalTrials.gov Identifier: NCT03506191|
Recruitment Status : Unknown
Verified July 2018 by Adrien Bouglé, Groupe Hospitalier Pitie-Salpetriere.
Recruitment status was: Active, not recruiting
First Posted : April 24, 2018
Last Update Posted : August 1, 2018
Pneumonia is a major cause of ICU admission, or may complicate ICU course. Among the causative pathogens, Stenotrophomonas Maltophilia is a rare pathogen, but affects usually patients with chronic pulmonary co-morbidities, or with long duration of mechanical ventilation and multiples treatment with broad spectrum antimicrobial therapy. However, there are only a paucity of data regarding epidemiology, impact and outcome of Pneumonia due to Stenotrophomonas Maltophilia in critically ill patients.
Primary objective was to study factors associated with mortality in case of Pneumonia due to Stenotrophomonas Maltophilia. Secondary objectives were to describe factors associated with morbidity of Pneumonia due to Stenotrophomonas Maltophilia (duration of mechanical ventilation, ICU length of stay), and to report the characteristics of critically ill patients presenting Pneumonia due to Stenotrophomonas Maltophilia.
|Condition or disease|
|Pneumonia, Ventilator-Associated Stenotrophomonas Infection Critical Illness Pneumonia, Bacterial|
|Study Type :||Observational|
|Estimated Enrollment :||300 participants|
|Official Title:||Pneumonia Due to Stenotrophomonas Maltophilia in Intensive Care Units: a Multicentre Retrospective Study|
|Actual Study Start Date :||January 1, 2017|
|Actual Primary Completion Date :||July 30, 2018|
|Estimated Study Completion Date :||September 30, 2018|
- Treatment failure [ Time Frame: Day 30 ]Treatment failure is defined as composite of death and recurrence of pneumonia due to Stenotrophomonas Maltophilia within 30 days of the first episode
- Duration of mechanical ventilation [ Time Frame: Day 30 ]Number of days under mechanical ventilation
- Recurrence of pneumonia due to Stenotrophomonas Maltophilia [ Time Frame: Day 30 ]New onset of pneumonia due to Stenotrophomonas Maltophilia
- Mortality [ Time Frame: Day 30 ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03506191
|Anesthesiology and Critical Care Medicine, Groupe Hospitalier Pitié-Salpêtrière|
|Paris, Ile-de-France, France, 75013|
|Réanimation Polyvalente CHR Metz-Thionville|
|Department of Anesthesiology and Critical Care Medicine, University Hospital of NANCY|
|Nancy, France, 54500|
|Department of Anesthesiology and Critical Care Medicine, University Hospital of Strasbourg|
|Study Director:||Adrien Bouglé, MD||APHP|
|Principal Investigator:||Philippe Guerci, MD||CHRU NANCY|