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Evaluation of Dysphagia by 6-chnnel Surface Electromyography

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ClinicalTrials.gov Identifier: NCT03494361
Recruitment Status : Completed
First Posted : April 11, 2018
Last Update Posted : July 23, 2020
Sponsor:
Information provided by (Responsible Party):
Ju Seok Ryu, Seoul National University Hospital

Brief Summary:

The natural process of aging affects a few very specific timing parameters such as swallow reaction time and hyoid one movement velocity.

Many swallow timing and bolus transit parameters appear to be unaffected by aging. We want to know the changes of kinematic variables according to the aging process.

First hypothesis: There are probably be a protection mechanism that blocks functional loss progressing to kinematic abnormality. Muscle activation sequence change (i.e duration or amplitude) of the oropharyngeal muscles play an important role.

Second hypothesis: Age-related differences in muscle activation patterns will also appear differently depending on the characteristics of swallowed food.


Condition or disease
Deglutition Disorders

Detailed Description:

Inclusion criteria

Inclusion criteria of healthy older adults : Age > 60, without dysphagia, comorbidity

Inclusion criteria of young control group

: Age < 60, without dysphagia, comorbidity

No prior history of swallowing difficulty or history of central nervous system disease, and none were taking medication that are known to affect swallowing.

Surface EMG was performed at bilateral suprahyoid, thyrohyoid, sternothyroid and pharyngeal constrictors. The latency of activation and termination was checked.

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Study Type : Observational
Actual Enrollment : 40 participants
Observational Model: Other
Time Perspective: Prospective
Official Title: Evaluation of Dysphagia by 6-chnnel Surface Electromyography and Preliminary Study for Design 6-channel Electrical Stimulation
Actual Study Start Date : July 4, 2016
Actual Primary Completion Date : November 21, 2017
Actual Study Completion Date : November 21, 2017

Resource links provided by the National Library of Medicine


Group/Cohort
Young normal group
normal participants below 60 years
Old normal group
normal participants above 60 years



Primary Outcome Measures :
  1. Latency [ Time Frame: once at study, when patient enrolled ]
    the latency of muscular activation


Secondary Outcome Measures :
  1. duration [ Time Frame: once at study, when patient enrolled ]
    the contractile duration of evaluated muscles



Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Sampling Method:   Non-Probability Sample
Study Population
Healthy participants
Criteria

Inclusion Criteria of old group

  • Age > 60, without dysphagia, comorbidity

Inclusion Criteria of young control group

  • Age < 60, without dysphagia, comorbidity
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Responsible Party: Ju Seok Ryu, associate professor, Seoul National University Hospital
ClinicalTrials.gov Identifier: NCT03494361    
Other Study ID Numbers: B-1604/344-003
First Posted: April 11, 2018    Key Record Dates
Last Update Posted: July 23, 2020
Last Verified: July 2020

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Ju Seok Ryu, Seoul National University Hospital:
deglutition disorders
electromyography
Additional relevant MeSH terms:
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Deglutition Disorders
Esophageal Diseases
Gastrointestinal Diseases
Digestive System Diseases
Pharyngeal Diseases
Otorhinolaryngologic Diseases