Pilot Study to Examine Health Effects of Daylight Exposure on Dementia Patients
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|ClinicalTrials.gov Identifier: NCT03483896|
Recruitment Status : Completed
First Posted : March 30, 2018
Results First Posted : March 29, 2019
Last Update Posted : March 29, 2019
|Condition or disease||Intervention/treatment||Phase|
|Dementia Depression Behavior Disorders||Other: Daylight Intervention||Not Applicable|
Exposure to sufficient daylight indoors is a novel and potentially effective nonpharmacological treatment option for reducing depression and other neuropsychiatric symptoms for people living with dementia in long term care facilities. However, there are currently no minimum requirements for daylight access in care facilities. In urban settings, it is common for residents to spend the majority of the day indoors, illuminated by electrical light sources that deliver light with significantly lower intensities and reduced spectrum compared with daylight.
A 12-week pilot study was conducted in 8 dementia care facilities involving (n = 83) participants addressing the hypothesis that an intervention increasing indoor exposure to daylight will reduce depression and other neuropsychiatric symptoms. At 4 facilities, staff was enlisted to increase daylight exposure by taking participants to a perimeter room with daylight exposure for socialization in the morning (8:00 - 10:00 AM) each day. At the other 4 facilities, a control group were taken to a similar sized area without daylight for socialization under typical electrical lighting conditions. Outcome measures for depression and other neuropsychiatric symptoms were taken at the beginning and end of the 12-week study.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||83 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Primary Purpose:||Basic Science|
|Official Title:||Pilot Study to Examine the Effects of Indoor Daylight Exposure on Depression and Other Neuropsychiatric Symptoms in People Living With Dementia in Long Term Care Facilities|
|Actual Study Start Date :||January 30, 2017|
|Actual Primary Completion Date :||May 10, 2017|
|Actual Study Completion Date :||June 5, 2017|
No Intervention: Control
At the 4 facilities in the control arm, participants received the usual care. During the period from 8:00 - 10:00 AM each day, the control group was taken to a similar sized area indoors (without daylight) for socialization under typical electrical lighting conditions.
Active Comparator: Daylight Intervention
At the 4 facilities in the active light intervention arm, staff increased the daylight exposure of participants by taking them to the perimeter zone of a daylit room from 8:00 to 10:00 AM for socialization over a period of 12 weeks. The perimeter zone was defined to be the region of the room within 3 meters from windows. The intervention was administered each day (7 days / week) over the duration of the study.
Other: Daylight Intervention
Staff increased the daylight exposure of participants by taking them to the perimeter zone of a daylit room from 8:00 to 10:00 AM for socialization over a period of 12 weeks. The perimeter zone was defined to be the region of the room within 3 meters from windows. The intervention was administered each day (7 days / week) over the duration of the study.
- Change in Cornell Scale for Depression in Dementia (CSDD) [ Time Frame: A CSDD score was taken at the beginning of the 12-week study and once again at the end of the 12-week study. ]The Cornell Scale for Depression in Dementia (CSDD) was used to measure depression. The CSDD is designed for the assessment of depression in older people with dementia who can at least communicate basic needs. The CSDD scale ranges from 0 to 38, with higher scores indicating higher levels of depression. Scores above 10 indicate a probable major depression. Scores above 18 indicate a definite major depression. Scores below 6 are associated with absence of significant depressive symptoms.
- Change in Neuropsychiatric Inventory Nursing Home Version (NPI-NH) [ Time Frame: A NPI-NH score was taken at the beginning of the 12-week study and once again at the end of the 12-week study. ]The Neuropsychiatric Inventory Nursing Home Version (NPI-NH) was used to measure neuropsychiatric symptomatology. The NPI-NH is a scale designed for assessment of people with dementia residing in extended care facilities. The NPI-NH includes ten behavioral areas (delusions, hallucinations, agitation/aggression, depression/dysphoria, anxiety, elation/euphoria, apathy/indifference, disinhibition, irritability/lability, aberrant motor behavior) and two types of neurovegetative changes (sleep and nighttime behavior disorders, appetite and eating disorders). Each of the 12 areas is scored on a subscale ranging from 0-12, where higher scores indicate greater neuropsychiatric symptomatology. A summary score is obtained from summing all 12 subscale scores. The summary score ranges from 0 - 144, where higher scores indicate greater neuropsychiatric symptomatology.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03483896
|United States, California|
|Alhambra Dementia Care|
|Alhambra, California, United States, 91801|
|Sierra Vista Memory Care Community|
|Azusa, California, United States, 91702|
|Calabasas Memory Care Community|
|Calabasas, California, United States, 91302|
|Costa Mesa Dementia Care|
|Costa Mesa, California, United States, 92627|
|Los Angeles Dementia Care (Beverly Place)|
|Los Angeles, California, United States, 90048|
|Redondo Beach Dementia Care (Beach Cities)|
|Redondo Beach, California, United States, 90277|
|San Juan Capistrano Memory Care Community|
|San Juan Capistrano, California, United States, 92675|
|Tustin Hacienda Memory Care Community|
|Tustin, California, United States, 92780|
|Principal Investigator:||Kyle Konis, Ph.D||University of Southern California|