Body Parameters as an Independent Predictor of Acute Pancreatitis
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|ClinicalTrials.gov Identifier: NCT03482921|
Recruitment Status : Completed
First Posted : March 29, 2018
Last Update Posted : March 29, 2018
|Condition or disease|
Acute pancreatitis (AP) is a sudden inflammation of the pancreas. However, one-fifth of patients may develop severe complications with a mortality between 10%-20% It remains a difficulty to find an effective method for prediction of severity of AP at early stage.
It is well-established that obesity (defined as body mass index[BMI]>30kg/m2 by the World Health Organization) is a risk factor for AP and increases the incidence of systemic complication, motality. There are a lot of parameters related to saropenic obesity, including areas of visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), skeletal muscle tissue (SMT), and VAT/SMT ratio. it is unclear which parameter is the best predictor of severe AP. Thus, this study is aimed to investigate the association between these parameters and AP severity and find the best predictor of AP.
|Study Type :||Observational [Patient Registry]|
|Actual Enrollment :||1662 participants|
|Target Follow-Up Duration:||7 Years|
|Official Title:||Body Parameters as an Independent Predictor of Acute Pancreatitis: A Propensity Score-matched Case-control Study|
|Actual Study Start Date :||December 1, 2017|
|Actual Primary Completion Date :||February 12, 2018|
|Actual Study Completion Date :||March 22, 2018|
- Comparisons of variables according to AP severity [ Time Frame: the physical examination data in the year of 2017 ]Comparisons of variables according to AP severity by one-way analysis of variance (ANOVA) and Likelihood Ratio
- Relationships between VAT and severity outcomes Relationships between VAT and severity outcomes Relationships between VAT and severity outcomes Relationships between body parameters and severity outcomes [ Time Frame: the physical examination data in the year of 2017 ]Relationships between VAT and severity outcomes by Likelihood Ratio
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Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03482921
|Ningbo NO.1 hospital|
|Ningbo, Zhejiang, China, 315010|
|Principal Investigator:||Lei Xu, Dr||Department of gastroenterology, Ningbo No.1 Hospital, Ningbo, China|