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Meir Medical Center Rheumatologic Biobank

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details. Identifier: NCT03473912
Recruitment Status : Recruiting
First Posted : March 22, 2018
Last Update Posted : March 11, 2019
Information provided by (Responsible Party):
Meir Medical Center

Brief Summary:
Serum, synovial fluid and skin biopsies from patients will be collected to the biobank with rheumatoid diseases. These samples will later be used for clinical and basic research, following approval of each specific study by the IRB. The investigators intend to extract protein, DNA and RNA from each sample.

Condition or disease
Rheumatoid Arthritis Lupus Erythematosus, Systemic Systemic Sclerosis IgG4-related Disease Sjogren's Syndrome

  Show Detailed Description

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Study Type : Observational [Patient Registry]
Estimated Enrollment : 500 participants
Observational Model: Cohort
Time Perspective: Prospective
Target Follow-Up Duration: 20 Years
Official Title: Rheumatologic Biobank for Clinical and Basic Research: Isolation, Extraction and Storage of Protein, DNA and RNA Extracted From Tissues of Patients With Rheumatoid Diseases
Actual Study Start Date : April 16, 2018
Estimated Primary Completion Date : November 2037
Estimated Study Completion Date : November 2037

RA patients
before or after medication
Systemic sclerosis patients
before or after medication
IgG4 RD patients
before or after medication
Lupus patients
before or after medication

Primary Outcome Measures :
  1. collecting samples [ Time Frame: 20 years ]
    IgG4-related disease patients

Biospecimen Retention:   Samples With DNA
blood, synovial fluid and skin biopsies.

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   18 Years to 120 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
patients of our rheumatological clinic which have a rheumatolid condition and are willing to sign an informed consent.

Inclusion Criteria:

  • above 18 years of age
  • willing to sign informed consent
  • have a rheumatoid condition

Exclusion Criteria:


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT03473912

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Contact: Yair Levy, Prof. 972-9-7471524
Contact: Noa Rabinowicz, Dr. 972-9-7471992

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Meir Medical Center Recruiting
Kfar Saba, Israel
Contact: Noa Rabinowicz, PhD    972-9-7471992   
Contact: Yair Levy, Prof    972-9-7471936   
Sponsors and Collaborators
Meir Medical Center
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Principal Investigator: Yair Levy, Prof. Meir Medical Center

Additional Information:

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Responsible Party: Meir Medical Center Identifier: NCT03473912     History of Changes
Other Study ID Numbers: MMC17-0116CTIL
First Posted: March 22, 2018    Key Record Dates
Last Update Posted: March 11, 2019
Last Verified: March 2019
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: Undecided
Plan Description: we might share samples (serum, DNA, RNA..) but not patient personal details as the samples will be coded.

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Additional relevant MeSH terms:
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Mouth Diseases
Dry Eye Syndromes
Sjogren's Syndrome
Scleroderma, Systemic
Scleroderma, Diffuse
Lupus Erythematosus, Systemic
Immunoglobulin G4-Related Disease
Joint Diseases
Musculoskeletal Diseases
Arthritis, Rheumatoid
Rheumatic Diseases
Connective Tissue Diseases
Autoimmune Diseases
Immune System Diseases
Skin Diseases
Salivary Gland Diseases
Stomatognathic Diseases
Lacrimal Apparatus Diseases
Eye Diseases