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Trial record 10 of 626 for:    transvaginal

Transvaginal Ultrasonography Guided Embryo Transfer

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ClinicalTrials.gov Identifier: NCT03473028
Recruitment Status : Not yet recruiting
First Posted : March 21, 2018
Last Update Posted : March 21, 2018
Sponsor:
Information provided by (Responsible Party):
sarah mohamed hassan, Kasr El Aini Hospital

Brief Summary:
to evaluate the value of using transvaginal ultrasound guided embryo transfer in obese patients undergoing in vitro fertilization.

Condition or disease Intervention/treatment Phase
Infertility, Female Procedure: transabdominal ultrasound guided embryo transfer Procedure: transvaginal ultrasound guided embryo transfer Phase 2 Phase 3

Detailed Description:
The 800 participants with body mass index more than 40 kg/m2 were randomly allocated to two groups of equal size using an automated web-based randomization system. The first group 400 patient undergoing the transabdominal-guided embryo transfer, the second group 400 patient undergoing transvaginal-guided embryo transfer.

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 800 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Intervention Model Description: randomized controlled trial
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Could Transvaginal Ultrasonography Guided Embryo Transfer Improves Pregnancy Outcome in Obese Patients Undergoing Intracytoplasmic Sperm Inoculation? Randomized Controlled Study
Estimated Study Start Date : April 2018
Estimated Primary Completion Date : August 2019
Estimated Study Completion Date : August 2019

Resource links provided by the National Library of Medicine


Arm Intervention/treatment
Active Comparator: transabdominal ultrasound
400 obese female undergo transabdominal ultrasound guided embryo transfer
Procedure: transabdominal ultrasound guided embryo transfer
400 female with body mass index more than 35 undergo transabdominal ultrasound guided embryo transfer

Active Comparator: transvaginal group
400 obese female undergo transvaginal ultrasound guided embryo transfer
Procedure: transvaginal ultrasound guided embryo transfer
400 female with body mass index more than 35 undergo transvaginal ultrasound guided embryo transfer




Primary Outcome Measures :
  1. clinical pregnancy rate` [ Time Frame: 4 weeks following embryo transfer ]
    the presence of at least one intrauterine gestational sac with viable fetus.



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Ages Eligible for Study:   25 Years to 40 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • BMI more than 35, good ovarian reserve, unexplained infertility more than 3 years.

Exclusion Criteria:

  • severe male factor of infertility,uterine factor of infertility excluded by ultrasonography and hysteroscopy ,ovarian endometrioma or patients with poly cystic ovary syndrome, obesity caused by abnormal endocrine function (thyroid or adrenal disorder)

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03473028


Locations
Egypt
Kasr El Ainiy Hospital
Cairo, Egypt, 11562
Sponsors and Collaborators
Kasr El Aini Hospital

Responsible Party: sarah mohamed hassan, lecturer of obstetrics and gynecology, Kasr El Aini Hospital
ClinicalTrials.gov Identifier: NCT03473028     History of Changes
Other Study ID Numbers: 2019
First Posted: March 21, 2018    Key Record Dates
Last Update Posted: March 21, 2018
Last Verified: March 2018

Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No

Keywords provided by sarah mohamed hassan, Kasr El Aini Hospital:
obesity
embryo transfer
invitro fertilization

Additional relevant MeSH terms:
Infertility
Infertility, Female
Genital Diseases, Male
Genital Diseases, Female