Retinal Metabolic Imaging in a Diverse Population
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|ClinicalTrials.gov Identifier: NCT03442816|
Recruitment Status : Recruiting
First Posted : February 22, 2018
Last Update Posted : February 22, 2018
|Condition or disease||Intervention/treatment||Phase|
|Technical Capabilities of the Device||Device: MHRC Camera||Not Applicable|
Hyperspectral retinal imaging results from several consecutive images taken while the filter scans a wide spectral range to obtain one spectrum for each image pixel. The combination of imaging and spectroscopy offered by hyperspectral imaging makes it possible to identify and quantify several specific biomolecules in the retina and the optic nerve, thus paving the way for metabolic imaging of the fundus. Subsequent analysis of the light signal with algorithms and image analysis software tools permits extracting molecular information modulated according to the underlying pathology. This technique thus permits direct, non-invasive and inexpensive diagnosis of pathologies of the retina and systemic pathologies presenting manifestations in the eye.
In this research project, Optina Diagnostics aims to evaluate in a clinical context a novel Metabolic Hyperspectral Retinal Camera (MHRC) based on a mydriatic camera customized for observation of the fundus in combination with a tunable filter, i.e., one permitting selection of a specific wavelength, in order to provide monochromatic light in the visible and near infrared spectrum (energy spectrum between 450 and 900 nm).
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||80 participants|
|Intervention Model:||Single Group Assignment|
|Intervention Model Description:||Subjects will undergo 1) an ophthalmic evaluation and 2) an evaluation with the device (camera)|
|Masking:||None (Open Label)|
|Official Title:||Evaluation of a Metabolic Hyperspectral Retinal Camera (MHRC) in Spectrally Resolved Reflectance and Fluorescence Imaging in a Diverse Population|
|Actual Study Start Date :||July 5, 2017|
|Estimated Primary Completion Date :||June 2018|
|Estimated Study Completion Date :||June 2018|
Experimental: MHRC camera
Subjects will undergo a retina imaging session with the MHRC camera.
Device: MHRC Camera
Evaluate the technical capabilities of the device to obtain quality images in reflectance and fluorescence imaging modes in a diverse population.
- Quality images in reflectance and fluorescence [ Time Frame: 1 day visit ]Evaluate the technical capabilities of the device to obtain quality images in reflectance and fluorescence imaging modes in a diverse population .
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03442816
|Contact: David Lapointeemail@example.com|
|Contact: Anne-Marie Bédardfirstname.lastname@example.org|
|Sunnybrook Health Sciences Centre||Recruiting|
|Toronto, Ontario, Canada, M4N 3M5|
|Contact: Charlene Muller 416-480-5091 Charlene.Muller@sunnybrook.ca|
|Principal Investigator: Peter Kertes, MD|
|Principal Investigator:||Peter Kertes, MD||Sunnybrook Health Sciences Centre|