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Trial record 26 of 531 for:    Taste Disorders

The Relationship Between Salt Restriction and Taste Sensitivity in Patients With Chronic Kidney Disease

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ClinicalTrials.gov Identifier: NCT03397550
Recruitment Status : Not yet recruiting
First Posted : January 12, 2018
Last Update Posted : January 16, 2018
Sponsor:
Information provided by (Responsible Party):
Dong Jie, Peking University First Hospital

Brief Summary:
The compliance of salt restriction in patients with CKD may be associated with taste sensitivity.

Condition or disease Intervention/treatment
Renal Insufficiency, Chronic Chronic Kidney Diseases Other: salt restriction education

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Study Type : Observational
Estimated Enrollment : 100 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: The Relationship Between Salt Restriction and Taste Sensitivity in Patients With Chronic Kidney Disease
Estimated Study Start Date : January 2018
Estimated Primary Completion Date : January 2019
Estimated Study Completion Date : April 2019

Resource links provided by the National Library of Medicine



Intervention Details:
  • Other: salt restriction education
    Salt intake target:<5g/d Method:the standard salt restriction education will be lasting for 10-15 minutes by oral explanation at baseline.


Primary Outcome Measures :
  1. ratings of taste sensitivity assessed by the ISO method of investigating sensitivity of taste(ISO 3972:1991) [ Time Frame: up to 12 weeks after intervention ]

    Taste sensitivity is measured by five taste solutions(salty、sour、bitter、sweet、umami). Every taste solution contains 8 different concentration. Detection , recognition and difference thresholds will be measured .Their definitions are as bellow.

    Detection threshold:minimum value of sensory stimulus needed to give rise to a sensation. The sensation need not be identified.

    Recognition threshold:minimum value of a sensory stimulus permitting identification of the sensation perceived.

    Difference threshold:value of the smallest perceptible difference in the physical intensity of a stimulus.




Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 80 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Sampling Method:   Non-Probability Sample
Study Population
stage 3-5 CKD patients
Criteria

Inclusion Criteria:

  • stage 3-5 CKD patients
  • clinical stable

Exclusion Criteria:

  • renal replacement therapy
  • cancer
  • systemic infection
  • Alzheimer's disease
  • acute cardiovascular events, active hepatitis
  • all other study-obstructive conditions

Publications of Results:
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Responsible Party: Dong Jie, Nephrology chief physician, Peking University First Hospital
ClinicalTrials.gov Identifier: NCT03397550     History of Changes
Other Study ID Numbers: pekingUFH-cn
First Posted: January 12, 2018    Key Record Dates
Last Update Posted: January 16, 2018
Last Verified: January 2018
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: Undecided

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No

Keywords provided by Dong Jie, Peking University First Hospital:
taste threshold
salt restriction

Additional relevant MeSH terms:
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Kidney Diseases
Renal Insufficiency, Chronic
Renal Insufficiency
Urologic Diseases