Effects of Green Coffee Extract Supplementation on Adropin, Irisin, Vaspine,Systemic Inflammation and Oxidative Stress in Breast Cancer Survivors
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ClinicalTrials.gov Identifier: NCT03395561
Recruitment Status : Unknown
Verified December 2017 by Dr Azita Hekmatdoost, National Nutrition and Food Technology Institute. Recruitment status was: Recruiting
First Posted : January 10, 2018
Last Update Posted : January 10, 2018
National Nutrition and Food Technology Institute
Information provided by (Responsible Party):
Dr Azita Hekmatdoost, National Nutrition and Food Technology Institute
To study the effects of green coffee supplement on adropin, irisin, vaspine, systemic inflammation and oxidative stress in breast cancer survivors.50 breast cancer survivors who their treatment is over and referred to follow breast cancer clinic with will be randomly allocated to receive placebos or 2 capsules green coffe for 12 weeks; both groups will be advised to adherence the investigators' diet and exercise program too. At the first and the end of the intervention, adropin, irisin, vaspine, systemic inflammation and oxidative stress will be assessed and compared between groups.
Tumor necrosis factor alpha [ Time Frame: 12 weeks ]
assessed by ELISA
Interleukin 6 [ Time Frame: 12 weeks ]
assessed by ELISA
Secondary Outcome Measures :
body mass index [ Time Frame: 12 weeks ]
The body mass index (BMI) or Quetelet index is a value derived from the mass (weight) and height of an individual. The BMI is defined as the body mass divided by the square of the body height, and is universally expressed in units of kg/m2, resulting from mass in kilograms and height in metres.
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Layout table for eligibility information
Ages Eligible for Study:
20 Years to 70 Years (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Age of 18 to 70 years
Body Mass Index (BMI) between 25-40 treatment is over
Taking any kind of supplement for weight reduction